C3

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C3

A diagnostic category based on the NHSBSP guidelines for reporting FNAC (fine needle aspiration cytology) of breast lesions. C3s have most of the characteristics described in C2s, but also have features not usually present in benign smears and have one or more of the following features:
(1) Crowded, enlarged nuclei with overlapping in three-dimensional groups or sheets;
(2) Loss of cellular cohesion;
(3) Nuclear pleomorphism;
(4) Chromatin clumping.
 
C3 cellularity may be normal or increased and large bare nuclei may be seen, as well as nuclear pleomorphism and dissociation.

Examples, C3
Epithelial hyperplasia with or without atypia, fibroadenoma/fibroadenomatoid change, gynaecomastia, papilloma, hormonal changes, radial scar, atypical apocrine lesion, columnar cell change, lobular lesions (e.g., atypical lobular hyperplasi), certain carcinomas (e.g., tubular carcinoma, cribriform carcinoma).

complement deficiency

A state in which any of the complement proteins is subnormal
Complement deficiencies–associated disorders
C1
C1r    SLE, renal disease, repeated infections
C1s    SLE
C2    SLE, vasculitis, membranoproliferative glomerulonephritis, dermatomyositis
C3 Repeated infections
C4 SLE
C5 SLE, gonococcal disease
C6 Relapsing meningococcal meningitis, gonococcal infection
C7 Raynaud's disease, chronic renal disease, gonococcal infection
C8 SLE, gonococcal infection

C3

The most abundant and functionally diverse component of the complement system.C3 has two main allotypes F (fast) and S (slow). In kidney transplant patients it has been found that C3 S/S recipients have a better long-term outcome when grafted with a C3 F/F or a C3 F/S/ kidney than with a C3 S/SF kidney.

C3

the third component of complement; a β protein. Split into two fragments, C3a and C3b, by C3 convertase which is triggered via the classical or alternative pathway of complement activation. An inherited deficiency occurs in Brittany spaniels and very low serum levels occur in some Finnish-Landrace lambs. See also complement.
References in periodicals archive ?
The American Council of Life Insurers has received little feedback from its 377 member companies on the implementation of C-3 Phase II, other than that the companies are fully complying with its requirements and are initiating the necessary changes to implement it, according to ACLI Spokesman Whit Cornman.
While the NAIC has heard comments that the implementation was both costly and time-consuming, the organization also received feedback that C-3 Phase II is "a necessary step in the right direction.
Lamson believes the large variable annuity writers already were doing the types of things required by C-3 Phase II in their businesses, while the small-to-medium-size writers weren't able to follow suit because of lesser technology, time and manpower.
Companies that do not comply with C-3 Phase II requirements will no longer be able to sell variable annuities.
Hartford Life has been prepared for the C-3 Phase II initiation for some time, the company said.
Companies likely will run C-3 Phase II once per quarter.
Security Benefit's run time for C-3 Phase II was four days, using nine computers.
18 Valuation Actuary Symposium, noted the company used 65 computers and 192 hours of computing time--four days' worth--to complete the C-3 Phase II model installation, Gaule said.
American Ink Jet's recent development of its UV Gold fade-resistant ink system for the Encad NOVAJET(tm) printer, typifies the C-3 process.
In this way, C-3 puts all of its products - from inks, media, and other products through continuous re-evaluation and will upgrade each of its products according to each ongoing advance in archivability, waterfastness, color integrity, product purity, and numerous other traits which are under constant development.
Drilling is continuing on the C-3 and C-5 targets and assay results will be released as they become available.
Chairman, stated, "The results of the testing of the C-3 well confirm our interpretation of the extent and our determination of the commerciality of the "C" Area of the Zhao Dong Block.