Cryptococcus neoformans

(redirected from C neoformans)

Cryp·to·coc·cus ne·o·for·'mans

a species that causes cryptococcosis in humans and other mammals, particularly the cat family. Cells are spheric and reproduce by budding; a prominent feature is a polysaccharide capsule. Cryptococcus neoformans var. neoformans has a worldwide distribution and can often be isolated from weathered pigeon droppings. Cryptococcus neoformans var. gattii causes cryptococcosis in subtropical and tropical climates. This variety has been isolated from foliage and litter of species of eucalyptus.
Farlex Partner Medical Dictionary © Farlex 2012

Cryp·to·coc·cus ne·o·for·mans

(krip-tō-kokŭs nē-ō-fōrmanz)
Fungal species that causes cryptococcosis in humans and other mammals, particularly the cat family. Some species isolated from foliage of species of eucalyptus trees.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
The genus Cryptococcus contains at least 39 basidiomycetous fungal species, with C gattii and C neoformans being involved most commonly in infections in people and animals alike.
While C neoformans has a worldwide distribution often related to the presence of pigeon guano and soil rich in organic matter, C gattii has a more restricted distribution and is associated with the presence of various species of trees.
Molecular typing methods further divided Cryptococcus species into 8 genotypes: VNI to VNIV for C neoformans, and VGI to VGIV for C gattii.
The spectrum of diseases caused by C neoformans ranges from pulmonary infection to disseminated disease frequently involving the central nervous system, and occasionally skin and bone.
Three days later, the patient's ascitic fluid culture grew C neoformans. Subsequent search for disseminated disease included microbiological studies of cerebrospinal fluid (CSF), blood, and urine.
The respiratory tract is considered to be the usual port of entry of C neoformans. However, the gastrointestinal (GI) tract has been proposed as a potential site either following ingestion or possible direct inoculation of C neoformans into the blood stream following upper GI bleeding or overgrowth of fungus after antibiotic use.
grubii/neoformans; 251 (92.6%) of them were C neoformans var.
The cerebrospinal fluid culture grew C neoformans. The patient was treated with intravenous fluconazole.
(2-4) The primary reservoir of C neoformans is birds; their droppings allow for transmission to humans via inhalation.
None of the other dimorphic fungi have the propensity for central nervous system involvement that C neoformans does.
Secreted phospholipase has been proposed as a virulence determinant in C neoformans. Phospholipase production by the egg yolk plate method, and in vitro susceptibility to fluconazole by using the disk diffusion test were performed on 17 C neoformans isolates.
The etiologic agent of cryptococcosis is the hasidiomycetous yeast Cryptococcus neoforrnans, (3,4) with 3 varieties recognized initially, C neoformans var grubii, (5) C neoformans var neoformans, and C neoformans var gattii.