Caenorhabditis elegans

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Caenorhabditis elegans

(sē″nō-răb-dīt′ĭs ĕl′ă-gănz, -găns)
A roundworm, about 1 mm long. It is the first multicellular organism for which the full genome was sequenced. Its cells are used in studies of the molecular basis of development, aging, and fat metabolism.
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References in periodicals archive ?
C elegans are small, quick to grow, cheap and easy to maintain, making them good to work with.
In a high glucose environment, C elegans treated with rooibos extract exhibited an extended lifespan.
In this study, we investigated whether rooibos aqueous extract can protect C elegans against oxidative stress caused by the pro-oxidant juglone or a high glucose environment.
Researchers have discovered that after extended flights in space, a microscopic worm Caenorhabditis elegans (C elegans) undergoes genetic changes that help it to love longer.
Although neurodegeneration can easily be visualized in C elegans by labeling neurons with fluorescent markers such as FITC (fluorescein isothiocyanate), DiI (l,l'-dioctadecyl-3,3,3',3',-tetramethylindo-carbocyanine perchlorate), DiO (3,3'-diocta-decyloxa carbocyanine perchlorate), and DiD (1,1'-dioctadecyl-3,3,3',3'-tetramethyl-indodicarbocyanine perchlorate) (Tong and Burglin 2010), the direct role of adiposity on neurodegeneration has not been explored to date.
Avery's team targeted receptor molecules on the surface of the C elegans' pharynx.
When bathed in Prozac, C elegans responds in two obvious ways.
elegans remains uncertain, because one study has demonstrated that long telomeres promote increased lifespans in C elegans (Joeng et al.
The same phenomenon explains the rapid elongation of C elegans, says Austin.
we can figure out what they're doing in C elegans and apply that to a whole myriad of human genetic issues," says Waterston.
Now, David Zarkower of the University of Minnesota Medical School in Minneapolis and his coworkers have identified a gene called mab-3 that governs aspects of male development for C elegans, which is either male or hermaphroditic.
But in C elegans at least, GABA sometimes excites nerve cells, McIntire and his coauthors report in the July 22 NATURE.