are small, quick to grow, cheap and easy to maintain, making them good to work with.
In a high glucose environment, C elegans treated with rooibos extract exhibited an extended lifespan.
In this study, we investigated whether rooibos aqueous extract can protect C elegans against oxidative stress caused by the pro-oxidant juglone or a high glucose environment.
Researchers have discovered that after extended flights in space, a microscopic worm Caenorhabditis elegans (C elegans
) undergoes genetic changes that help it to love longer.
Although neurodegeneration can easily be visualized in C elegans
by labeling neurons with fluorescent markers such as FITC (fluorescein isothiocyanate), DiI (l,l'-dioctadecyl-3,3,3',3',-tetramethylindo-carbocyanine perchlorate), DiO (3,3'-diocta-decyloxa carbocyanine perchlorate), and DiD (1,1'-dioctadecyl-3,3,3',3'-tetramethyl-indodicarbocyanine perchlorate) (Tong and Burglin 2010), the direct role of adiposity on neurodegeneration has not been explored to date.
Avery's team targeted receptor molecules on the surface of the C elegans
When bathed in Prozac, C elegans
responds in two obvious ways.
elegans remains uncertain, because one study has demonstrated that long telomeres promote increased lifespans in C elegans
(Joeng et al.
The same phenomenon explains the rapid elongation of C elegans
, says Austin.
we can figure out what they're doing in C elegans
and apply that to a whole myriad of human genetic issues," says Waterston.
Now, David Zarkower of the University of Minnesota Medical School in Minneapolis and his coworkers have identified a gene called mab-3 that governs aspects of male development for C elegans
, which is either male or hermaphroditic.
But in C elegans
at least, GABA sometimes excites nerve cells, McIntire and his coauthors report in the July 22 NATURE.