Bystander Effect


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Immunology See Bystander suppression
Molecular biology The secondary effects on adjacent cells and tissues triggered by treatment of a primary target with a therapeutic agent.
Molecular medicine An anticancer effect of unknown origin evoked by some forms of gene therapy in which a treatment—e.g., p53 therapy—kills more tumour cells than can be accounted for by the number of cells actually expressing an inserted gene bystander effect
Psychology Bystander apathy A type of social phenomenon in which person ‘A' is less likely to assist a person 'B' in need of help, when other people are present, than when ‘A’ is alone
References in periodicals archive ?
Gourdie's team discovered a compound that targets the activity of channels in cell membranes responsible for controlling key aspects of the bystander effect.
'This bystander effect, in which people are too scared to perform First Aid, leads to the death of 10,000 Brits a year'
- Bystander effect of ADCs - How the presence of antigen expressing cells can induce additional efficacy of the ADC and can cause antigen negative cells to express cytotoxicity
The bystander effect refers to the finding that the more people present, the lower the likelihood that any one of them will help in an emergency situation (Latane & Darley, 1970).
An alternative perspective based on the bystander effect implies that the high participation of others may decrease an individual's charitable behavior.
A 2016 study published by Harvard Business Review , which mentions my experience with Ailes, identified three factors that contribute to employees' reluctance to speak up when they witness sexual harassment: Fear of retaliation; the "bystander effect" (we're less likely to come to the aid of victims when others are present); and a masculine culture that sees sexual harassment as acceptable.
With its base of Eisai's in-house developed eribulin, MORAb-202 demonstrates new generation ADC characteristics, namely, internalization into target cancer cells, an antitumor effect followed by a bystander effect after its releasing its drug payload, and aggregation inhibition.
The bystander effect, as it's known, became famous in the 1960s, following the tragic murder of Kitty Genovese.
The bystander effect, as it's known, became famous in the 1960s following the tragic murder of Kitty Genovese.
the bystander effect, as it's known, became fams ous in the 1960s following the tragic murder of Kitty Genovese.
The bystander effect is a phenomenon under study to understand why individuals either intervene or do not intervene when bullying and victimization is happening in front of them (Nichols, Perkins, Wellman, & Wellman, 2013).