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Abbreviation for biopsy.
Farlex Partner Medical Dictionary © Farlex 2012


(bi'op?se) [ bio- + -opsy],


A tissue sample removed from the body for microscopic examination, usually to establish a diagnosis. The tissue can be obtained surgically or by aspiration. The procedure can be guided by computed tomography, ultrasonography, magnetic resonance imaging, or radiography, or it can be performed without imaging, i.e., “blindly”.

aspiration biopsy

Needle biopsy.

blind biopsy

A biopsy taken without radiographic guidance or strong evidence of localized disease.

brush biopsy

The removal of cells from an organ by rubbing them loose.

cone biopsy

Removal of a cone shaped piece of tissue from the uterine cervix to diagnose or treat cervical diseases. The procedure may be performed with a scalpel, carbon dioxide (CO2) laser, or Loop Electrosurgical Excision Procedure (LEEP).

endometrial biopsy

The removal of a sample of uterine endometrium for microscopic study. The procedure is commonly used in fertility assessment to confirm ovulation and to determine the cause of dysfunctional or postmenopausal bleeding.
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fine needle aspiration biopsy

Abbreviation: FNA biopsy
The removal of cells or tissue through a long, narrow-gauge needle with or without radiological guidance.
See: illustration

fine-needle nonaspiration biopsy

Fine-needle capillary sampling.

liver biopsy

1. The percutaneous removal of tissue from the liver with a large-bore needle that captures a core of tissue.
2. A wedge of the liver obtained during laparotomy or laparoscopy.

muscle biopsy

The removal of muscle tissue for microscopic examination and chemical analysis.

needle biopsy

The withdrawal of fluid or tissue by means of negative pressure applied with needle and syringe.
Synonym: aspiration biopsy

percutaneous breast biopsy

Use of a directional, high-speed, rotating cutter attached to a vacuum source to gather multiple contiguous core samples of breast tissue through a single point of insertion. This minimally invasive procedure is usually performed under local anesthesia, using stereotactic imaging or real-time ultrasonography.

percutaneous renal biopsy

Obtaining renal tissue for analysis with a needle inserted through the skin, usually done after the kidney has been localized by ultrasound, computed tomography, or angiography. This technique is used to establish a diagnosis of renal dysfunction, determine prognosis in patients with renal disease, evaluate the extent of renal injury, and determine appropriate therapy. The most common complication is urinary bleeding, which tends to clear gradually over several days.

percutaneous transthoracic needle aspiration biopsy

Use of a radiographically guided aspiration needle to obtain a sample of tissue in cases of suspected pulmonary malignancies or other unknown lesions. Because of the risk of pneumothorax, the procedure is usually contraindicated in patients receiving mechanical ventilation.

punch biopsy

The removal of a small piece of tissue (usually of the skin) with a hollow, round cutting tool.

sentinel node biopsy

A technique for identifying the initial site of cancer metastasis. After injection of a radioactive tracer directly into the tumor mass, the tissue is massaged to encourage uptake of tracer by lymphatic vessels. A negative biopsy of the first node infiltrated by the tracer suggests that the malignancy has not yet spread to neighboring regional lymph nodes.

shave biopsy

Removal of a shallow layer of skin with a cutting instrument, e.g., a scalpel, sawing parallel to the skin surface. A shave biopsy may leave a small depression in the skin.


It should not be used to remove lesions suspected for melanoma or lesions that seem to have significant depth.

suction biopsy

A technique for obtaining tissue by aspiration, e.g., to obtain tissue from the mucosa of the stomach and intestines.

vacuum-assisted biopsy

A biopsy technique in which a hypodermic probe is placed through the skin into an organ of the body (such as the breast), and negative pressure is used to draw one or more samples into a chamber, where they are captured and removed for analysis under a microscope.
Medical Dictionary, © 2009 Farlex and Partners