ACADS

(redirected from Butyryl-coa dehydrogenase)
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ACADS

A gene on chromosome 12q24.31 that encodes a tetrameric mitochondrial flavoprotein of the acyl-CoA dehydrogenase family which catalyses the first step of the mitochondrial fatty acid beta-oxidation pathway.
 
Molecular pathology
Defects in ACADS cause acyl-CoA dehydrogenase short-chain deficiency.
References in periodicals archive ?
It is also likely that [H.sub.2]S disrupts fatty acid oxidation through inhibition of butyryl-CoA dehydrogenase. EMA may be formed via carboxylation of accumulated butyryl-CoA, catalyzed by propionyl-CoA carboxylase.
During the conversion of acetyl-CoA into butyryl-CoA thiolase crotonase 3-hydroxybutyryl-CoA dehydrogenase and butyryl-CoA dehydrogenase are played vital roles as key enzymes.