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Industrial solvent and purported health additive. Precursor in the synthesis of γ-hydroxybutyric acid.


n. Abbr. GBL
A chemical that has many industrial uses, especially as a solvent. It is a chemical precursor to gamma-hydroxybutyrate and is ingested illegally for its euphoriant and sedative effects.


(GBL) (gam'ă-byū'tir-ō-lak'tōn)
An industrial and household solvent that is readily metabolized after oral ingestion to gamma-hydroxybutyrate (GHB). Like GHB, it is marketed illicitly as a euphoriant, appetite suppressant, antidepressant, and sleep aid. It is more potent than GHB and has both a more rapid onset and a longer duration of action, but its pharmacologic and toxic properties are essentially the same: nausea, bradycardia, and central nervous system depression ranging from drowsiness and confusion to seizures, coma, and death. Dependency and severe withdrawal symptoms have been reported.
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FDA Issues Alert about Misuse of Consumer Products Containing Gamma Hydroxybutyric Acid (GHB), Gamma Butyrolactone (GBL), and 1,4 Butanediol (BD) (June 15, 1999) (Letter (PDF), Poster) (see also January 21, 1999 Talk Paper)
Nuclear maturation kinetics and in vitro embryo development of cattle oocytes prematured with butyrolactone I combined or not combined with roscovitine.
Wright had denied intentionally administering a substance which the body transforms into Gamma Butyrolactone, knowing she did not consent, with the intention of stupefying or overpowering her to enable himself or another to engage in sexual activity with her.
Tests made later revealed Gamma Butyrolactone ( better known as GHB ( was in her bloodstream.
Over three years Calder transported thousands of litres of the chemical gamma butyrolactone (GBL) to co-accused Jamie Greiman in California.
The report estimates the market size of 1,4-butanediol industry for major applications such as tetrahydrofuran, polybutylene terphthalate, gamma butyrolactone, polyurethane, and others.
We have isolated eight compounds from TLFA, they were all identified as lignans with dibenzyl butyrolactone structure (Xu et al.
Mr Llwyd said: "In August, the Advisory Council on the Misuse of Drugs recommended that gamma butyrolactone, or GBL for short, becomes a Class C substance.
Parthenogenetic activation and subsequent development of porcine oocytes activated by a combined electric pulse and butyrolactone I treatment.
Tests later revealed she had Gamma Butyrolactone, known as GHB ( a drug capable of affecting the central nervous system ( in her blood.
Wright, 36, of Eastgarth, Newbiggin Hall, Newcastle, denies intentionally administering a substance, which the body transforms into Gamma Butyrolactone, to the woman, knowing she did not consent and with the intention of stupefying or overpowering her so as to enable himself or another to engage in sexual activity involving her.