Butyrate supplementation also directly compounds the benefits offered by a ketogenic diet and exogenous ketone supplementation in a synergistic way.
The Plausible Benefits of Coupling Butyrate (Short Chain Fatty Acid) with BHB
Butyrate serves as a significant synergistic force for ketosis induction; BHB ligand interactions and pharmacology; and general health, fitness, and performance support.
Butyrate has also been shown to activate Nrf2 [172,173].
Mitsuyama et al., "Butyrate from bacterial fermentation of germinated barley foodstuff preserves intestinal barrier function in experimental colitis in the rat model," Journal of Gastroenterology and Hepatology, vol.
Chuang, "The HDAC inhibitor, sodium butyrate, stimulates neurogenesis in the ischemic brain," Journal of Neurochemistry, vol.
Yamawaki, "Antidepressant-like effect of sodium butyrate (HDAC inhibitor) and its molecular mechanism of action in the rat hippocampus," World Journal of Biological Psychiatry, vol.
[9.] Ahsan U, Cengiz O, Raza I, et al Sodium butyrate in chicken nutrition: the dynamics of performance, gut microbiota, gut morphology, and immunity.
Sodium butyrate maintains growth performance by regulating the immune response in broiler chickens.
Effect of butyrate on immune response of a chicken macrophage cell line.
The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition.
Effect of Sodium butyrate and zinc bacitracin on performance in broilers Treatments Growth Parameters phase SB-1 SB-0.5 1st Avg.