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a form of undifferentiated lymphoma, usually found in central Africa but also reported from other areas, and manifested most often as a large bone-destroying lesion in the jaw or as an abdominal mass. The epstein-barr virus (EB virus), a herpesvirus, has been isolated from Burkitt's lymphoma cells in culture, and has been implicated as a causative agent. Called also African lymphoma and Burkitt's tumor.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
Burkitt's lymphomaA tumour of B lymphocytes occurring mainly in Central Africa and New Guinea and associated with the Epstein Barr virus, spread by insects. It affects mainly the lower and upper jaws of young children but can affect most parts of the body. Burkitt's lymphoma was one of the first human tumours to be shown to be caused in this way. The tumour commonly spreads to the abdomen where large secondary masses may form, affecting the bowel. Immunosuppressive chemotherapy with cyclophosphamide or METHOTREXATE is apparently curative in 80% of early cases and about 40% of those with advanced, widespread disease. (Dennis Parsons Burkitt, 1911–93, English medical researcher, bran apostle, and Fellow of the Royal Society).
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
Burkitt's lymphomaa common cancer of African children, producing tumours of the jaw and facial bones and affecting the spleen and lymph nodes. It is caused by the Epstein-Barr virus.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005