Burkholderia mallei


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Burkholderia mallei

a bacterial species infectious to horses and donkeys, causing glanders and farcy.
Synonym(s): Pseudomonas mallei

Burkholderia mallei

A gram-negative bacterium which causes glanders in horses, donkeys and mules; it is not part of normal human flora.

Clinical findings
Human disease is rare, and follows exposure of mucocutaneous surfaces (eyes, mouth, nose) or skin cuts to infected animals, resulting in fever, skin abscesses, pneumonia and septicaemia, which, if untreated, is often fatal.

Burk·hol·der·i·a mal·le·i

(bŭrk-hol-der'ē-ă mal'ē-ī)
A bacterial species infectious to horses and donkeys, causing glanders and farcy.
Synonym(s): Pseudomonas mallei.
References in periodicals archive ?
Clinical features and laboratory diagnosis of infection with the potential bioterrorism agents burkholderia mallei and burkholderia pseudomallei.
van Rotterdam, "Multiplex qPCR for reliable detection and differentiation of Burkholderia mallei and Burkholderia pseudomallei'" BMC Infectious Diseases, vol.
Zacharia et al., "Serodiagnosis of Burkholderia mallei infections in horses: state-of-the-art and perspectives," Journal of Veterinary Medicine B, vol.
Brett, "Burkholderia mallei cluster 1 type VI secretion mutants exhibit growth and actin polymerization defects in RAW 264.7 murine macrophages," Infection and Immunity, vol.
(1) Observe DNA sequence mutations arising from an originally clonal isolate of Burkholderia mallei strain China 7 (ATCC 23744), and Burkholderia pseudomallei strain 668 when cultured under stressful conditions in the laboratory.
Burkholderia mallei is the etiologic agent of glanders, a disease primarily of equids, which is also communicable to man with fatal consequences.
Antibiotic susceptibility of 65 isolates of Burkholderia pseudomallei and Burkholderia mallei to 35 antimicrobial agents.
Actin-binding proteins from Burkholderia mallei and Burkholderia thailandensis can functionally compensate for the actin-based motility defect of a Burkholderia pseudomallei bimA mutant.
Bavarian Nordic said it had been selected by the Defense Threat Reduction Agency - which is part of the US Department of Defense - for the development of a vaccine against Burkholderia pseudomallei and Burkholderia mallei which are seen as potential threats to national security.
anthracis, Burkholderia mallei, and Burkholderia pseudomallei strains were received from either the CDC or the NIH Biodefense and Emerging Infections Research Resources Repository (BEI Resources, Bethesda, MD, USA).
Lazarus et al., "Identification of Burkholderia mallei and Burkholderia pseudomallei adhesins for human respiratory epithelial cells," BMC Microbiology, vol.
Brett, "Revised structures for the predominant O-polysaccharides expressed by Burkholderia pseudomallei and Burkholderia mallei" Carbohydrate Research, vol.