Burkholderia cepacia

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Burkholderia cepacia

a bacterial species found in rotted onions and in clinical specimens; commonly found in respiratory secretions in patients with cystic fibrosis, it is frequently resistant to many antibiotics.
Synonym(s): Pseudomonas cepacia

Burkholderia cepacia

formerly Pseudomonas cepacia. A group of bacteria found in the environment that are often resistant to common antibiotics. Immunocompromised persons or those with chronic lung disease, especially cystic fibrosis, are susceptible to infection. In patients without cystic fibrosis, B. cepacia infections are almost all nosocomial or related to IV drug abuse. Outbreaks have been related to intra-aortic balloon pumps, contaminated water sources, respiratory therapy equipment such as reusable electronic ventilator probes or contaminated disinfectants. A variety of approaches including strict segregation of cystic fibrosis patients based on the presence of this organism have been tried in order to reduce nosocomial transmission. Even a single significant nosocomial infection with B. cepacia may warrant investigation.

Burkholderia cepacia

A group of at least 17 Pseudomonas-like gram-negative bacteria found in the environment—e.g., plants, water, soil and in hospital—which may colonise the respiratory tract.

Clinical findings
May cause life-threatening pneumonia in patients with cystic fibrosis, chronic granulomatous disease and lung transplants; B cepacia may also cause urinary tract infections and infect sterile body sites.
 
Epidemiology
Transmitted by direct physical contact from contaminated environmental sources, fluids and medical devices, by aerosol or person-to-person.

Burkholderia cepacia

Pseudomonas cepacia Bacteriology A bacterium found in the environment–eg, plants, water, soil, and in hospital environment, which may colonize the respiratory tract of Pts with cystic fibrosis; transmitted by direct physical contact from contaminated environmental sources, fluids and medical devices and, by aerosol, person-to-person Clinical May cause life-threatening URIs in Pts with cystic fibrosis, chronic granulomatous disease; also associated with UTIs and may infect sterile body sites

Burk·hol·der·i·a ce·pa·ci·a

(bŭrk-hol-der'ē-ă sē-pā'shē-ă)
A bacterial species found in rotted onions and in clinical specimens; commonly found in respiratory secretions in patients with cystic fibrosis, it is frequently resistant to many antibiotics. Formerly known as Pseudomonas cepacia.
References in periodicals archive ?
Polyclonal outbreak of bloodstream infections caused by Burkholderia cepacia complex in hematology and bone marrow transplant outpatient units.
Taxonomy and identification of the Burkholderia cepacia complex.
That cluster also includes the species of the Burkholderia cepacia complex, the "pseudomallef group, and B.
Species abundance and diversity of Burkholderia cepacia complex in the environment.
The Burkholderia cepacia complex (BCC) encompasses at least 17 related Gram-Negative bacilli species as judged by different phenotypic and genotypic analyses.
The proteobacteria Burkholderia mallei and Burkholderia pseudomallei, distinct from the Burkholderia cepacia complex, cause melioidosis and glanders, respectively [1].
Burkholderia cepacia complex (BCC) is ubiquitous in our environment and has been recognized as a group of highly virulent organisms in Cystic fibrosis (CF) and chronic granulomatous disease (CGD).
Sustained endemicity of Burkholderia cepacia complex in a pediatric institution, associated with contaminated ultrasound gel.
Burkholderia cepacia complex (BCC) can be particularly devastating, highly virulent, cystic fibrosis (CF) pathogens that are also able to cause nosocomial infections among other groups of debilitated patients (1).
Nineteen out of twenty-eight referred isolates were initially identified as Burkholderia cepacia complex, four as Ralstonia species and five were not identified to the species level, thus reinforcing the need for molecular methods when attempting to definitively identify this genus.
The multifarious, multireplicon Burkholderia cepacia complex.