AKAP13

(redirected from Brx)
Also found in: Acronyms.

AKAP13

A gene on chromosome 15q24-q25 that encodes a member of the structurally diverse A-kinase anchor protein (AKAP) family, which binds to the regulatory subunits (RI/RII) of cAMP-dependent protein kinase A (PKA), confining PKA to discrete locations within the cell based on different targeting motifs. Alternative splicing of AKAP13 results in at least 3 transcript variants that encode different isoforms containing a dbl oncogene homology (DH) domain and a pleckstrin homology (PH) domain with various functions. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP-binding proteins, activating GTPase and resulting in signal transduction. The isoforms function as scaffolding proteins to co-ordinate a Rho-signalling pathway and function as PKA-anchoring proteins
References in periodicals archive ?
The BRX, like any other reticle with some type of holdover bars, can be used to range as well as shoot at incline angles.
By incorporating the BRX platform, OTA will be able to offer wireless carriers a powerful turnkey solution that will provide premium carrier-branded content coupled with a "pay-as-you-go" billing structure that works in conjunction with the carriers existing billing system.
Leftlane News, an automotive magazine, has revealed details of the 2010 Cadillac BRX crossover vehicle.
By utilizing BRX, wireless carriers are enabled in a cost effective way to profit from data services by eliminating revenue leaks and adding the ability to bill for premium content.
Lighting System At Nikari Para,Masjid Para,2B Chetla Rd Etc Slum Areas In Wd No 81 Brx.
Through its adaptable usage capture process and conditional formula-based rating engine, BRX can add billing records to existing bills or use alternate payment sources, such as Stored Value accounts.
It will share the platform with the Cadillac BRX and will be produced at Mexico's Ramos Arizpe factory.
Brixmor is a real estate investment trust listed on the New York Stock Exchange under the symbol BRX.
It will share its platform with the upcoming Cadillac BRX and will be manufactured in Mexico.
Quotation are invited for Augmentation Of Water Supply Lines At 9/84,11/18, 5/80,8/67b Etc Netaji Nagar,50,12/4e,1/11,12/4/1 Etc Khanpur Road Repairing Of Stand Post At 1/4 Suryanagar,5/64 Netajinagar 3/85, 2 Sanghati Colony Etc In Ward- No-98 Brx
M naskar rd, tollygunge agragami , nehury colony , wireless 2nd gate(ambagan ) etc in ward no -97, brx