Brunner glands


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Related to Brunner glands: Duodenal glands

du·o·de·nal glands

[TA]
small, branched, coiled tubular glands that occur mostly in the submucosa of the first third of the duodenum; they secrete human epidermal growth factor (urogastrone) as well as an alkaline mucoid substance that neutralizes gastric juice.

du·o·de·nal glands

(dū'ō-dē'năl glandz) [TA]
Small, branched, coiled tubular glands that occur mostly in the submucosa of the first third of the duodenum; they secrete an alkaline mucoid substance that serves to neutralize gastric juice.
Synonym(s): Brunner glands.

Brunner glands

(brun'er)
[Johann C. Brunner, Swiss anatomist, 1653–1727]
Compound glands of the duodenum and upper jejunum that are similar to the pyloric glands of the stomach. They are embedded in the submucosa and lined with columnar epithelium. They secrete alkaline mucus which neutralizes the hydrochloric acid entering the duodenum from the stomach.
Synonym: duodenal glands

Brunner,

Johann C., Swiss anatomist, 1653-1727.
Brunner gland hamartoma
Brunner glands - small glands that secrete a substance that neutralizes gastric juice. Synonym(s): duodenal glands
References in periodicals archive ?
Clinical Significance and Treatment.--As previously mentioned, owing to their larger size, Brunner gland hamartomas may cause GI hemorrhage or intestinal obstruction requiring endoscopic and sometimes surgical resection.
The concept of Brunner gland adenoma is very controversial and still a matter of ongoing debate.
Brunner gland cysts are very rare polypoid or nodular lesions of the duodenum characterized by a submucosal cystic dilation of the Brunner gland ducts.
These cells may differentiate toward the surface, forming areas of gastric foveolar metaplasia or downwards giving rise to Brunner gland hyperplasia or Brunner gland hamartoma.
This last finding is useful in differentiating a pyloric gland adenoma from Brunner gland lesions, especially in small biopsy specimens.
Brunner gland hyperplasia is associated with Chronic renal failure, chronic pancreatitis, duodenitis, peptic ulcer.
Brunner gland hyperplasia is an infrequently encountered polypoidal lesion in the proximal duodenum.
Brunner gland hyperplasia or adenomas are still rarer and pose diagnostic challenge.
Brunner gland hamartoma is a benign lesion, which can be treated by limited surgical resection or polypectomy.