Elephantiasis is caused by a variety of roundworms (filarial worms to be precise), which include Wucherereria bancrofti which causes almost 90 per cent of cases while Brugia malayi
accounts for most of the remaining 10 per cent.
In an experiment with rodents (Mastomys coucha) the crude extract from stem of Lantana by oral route shows antifilarial efficacy (Mishra et al., 2007) by killing 40% of adult Brugia malayi
parasites and sterilizing three fourth of the female worms.
An annotated reference Wolbachia genome was obtained from New England Biolabs (http://tools.neb.com/wolbachia, originating from infection of Brugia malayi
; Foster et al.
Hastaligin etkenleri; Wuchereria bancrofti, Brugia malayi
 It is caused by lymphatic dwelling nematodes namely Wuchereria bancrofti, Brugia malayi
and Brugia timori, and transmitted by the bite of infective mosquitoes.
Species Name Specimen Vector Collection Site Count Status Description Aedes (Hul.) 13 WNV Fire tub, japonicus cemetery urn, (Theobald, 1901) rock hole Aedes (Stg.) 127 DENV, CHIKV, Bamboo stump, albopictus ZIKV bamboo vase, (Skuse, 1894) concrete tub, creek, pan, iron kettle bombed area, cemetery urn, wooden tub Aedes (Tan.) togoi 149 JEV Bamboo stump, (Theobald, 1907) bucket, cement tank, ditch, fire tub, rock hole, tank in bombed area, wooden barrel Anopheles (Ano.) 15 Cement tank, koreicus Yamada seepage pool and Watanabe, 1918 Anopheles (Ano.) 31 Brugia malayi
Ditch, grassy sinensis s.l.
Given their role in health and disease, it is no surprise that they have a relevant role in the pathogenesis of filariasis caused by the lymphatic-dwelling nematodes Wuchereria bancrofti, Brugia malayi
, and B.
Mouse infection with Brugia malayi
(a filarial nematode that belongs to the order Spirurida, superfamily Filarioidea) also induces AAMs that strongly suppress T cell proliferation and have tissue repair functions [61, 62].
Lymphatic filariasis (LF) is a disease of considerable socio-economic burden in the tropics and sub-tropics and is caused by Wuchereria bancrofti, Brugia malayi
The major offending organisms in lymphatic filariasis are Wuchereria bancrofti and Brugia malayi
or Brugia timori.