Brugada syndrome


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Brugada syndrome

A family of autosomal dominant conditions which manifest themselves in young individuals—especially from southeast Asia—with no known heart problems or defects, who suffer sudden cardiac death or aborted sudden cardiac death.
 
EKG
Right bundle branch block; persistent ST-segment elevation in V1 to V3, unexplained by electrolyte disturbances; ischaemia; structural heart disease.
 
Management
Implantable defibrillator.

Brugada syndromes
Type—MIM Number—Defective gene    
Brugada-1—601144—SCN5A      
Brugada-2—611778—GPD1L-611778
Brugada-3—114205—CACNA1C-
Brugada-4—600003—CACNB2
Brugada-5—604433—KCNE3
Brugada-6—600235—SCN1B

Brugada syndrome

Cardiology A condition in which people with no known heart problems or defects suffer sudden cardiac death or aborted sudden cardiac death EKG Right bundle branch block, persistent ST-segment elevation in V1 to V3 unexplained by electrolyte disturbances, ischemia, structural heart disease Treatment Implantable defibrillator. See Long Q-T syndrome.

Brugada syndrome

(broo-gŏd′ă)
A rare hereditary syndrome, occasionally autosomal dominant, marked by right bundle branch block, S-T segment elevation in the right precordial leads of the ECG, and a high risk of sudden death from ventricular arrhythmias.
References in periodicals archive ?
Risk factors include family history of Brugada syndrome, male sex, Asian origin and fever.
General anesthesia for a patient with Brugada syndrome. Middle East J Anesthesiol 2012; 21:743-746.
Antzelevitch said he was very pleased to be able to address this timely meeting and particularly pleased to have the opportunity to discuss some of the most complex cardiovascular diseases like the Brugada Syndrome, which has caused so much distress to families like Hyla Molander.
Brugada syndrome is another rare syndrome that results from disease of ion channel fluxes in the ventricular myocardium.
* For patients with Brugada syndrome who have documented VT that has not resulted in cardiac arrest.
In Brugada syndrome, sodium flow is impaired due to a defective gene inherited from either parent.
Brugada syndrome is characterized by a typical electrocardiogram (ECG) abnormality in the right precordial leads and a high risk of ventricular fibrillation- (VF-) related sudden cardiac death.
We have recently read the case report by Ari and Ekici (1) with great interest and noted that this patient displayed electrocardiogram patterns characteristic of Brugada syndrome after a propafenone overdose with the intention of suicide.
At the hospital, the doctor reveals that Arthur has a high risk of having the same condition as his birth father Kush, Brugada syndrome. Dot is upset to hear Reverend Stevens is leaving, and she arranges to meet the new vicar and discuss the Harvest Festival.
It later transpires that he has life-threatening Brugada syndrome and it's inevitable that Arthur will develop it too.
Bangungot is known by many complicated medical names: acute hemorrhagic pancreatitis, sudden arrhythmic death syndrome or sudden adult death syndrome (SADS), bed death, sudden unexplained death syndrome (SUDS), Brugada Syndrome, and sudden unexpected nocturnal death syndrome (SUNDS).
There may be no structural cardiac abnormality (e.g., channelopathies like long or short QT syndrome or Brugada syndrome), a minimal structural abnormality (e.g., an accessory pathway causing Wolf Parkinson White syndrome) or a severe structural abnormality (e.g., ventricular septum defect with heart block).