Gomez, "Peripheral brown tumour
of hyperparathyroidism in the oral cavity," Oral Oncology Extra, vol.
Skeletal radiography revealed splaying of lower limb below the knee joint, decreased bone mineral density, thin cortices and several cystic brown tumours
in pelvis and calvarium presenting the initiation of von Recklinghausen disease of bone (Figure-1).
Mandible, clavicle, ribs, pelvis, long bones and hands 4.
Brown tumours are the end stage of primary or secondary hyperparathyroidism.
Based on these results, the osteolytic FDG avid bone lesions were classified as multiple brown tumours caused by primary hyperparathyroidism.
This case demonstrates that increased FDG uptake in clinically occult brown tumours can be misleading in the evaluation of a patient for malignancy.
Brown tumours of bone or osteoclastomata are highly vascular, lytic bone lesions representing a reparative cellular process rather than a neoplastic process usually seen in patients with hyperparathyroidism with hypercalcaemia.
Brown tumours exhibit no pathognomonic histological changes.
Brown tumours show a high accumulation of FDG, probably as a result of the presence of giant cells.
Brown tumours represent a reparative cellular process rather than a neoplastic process that shows lytic lesions.