BPTF(redirected from Bromodomain PHD Finger Transcription Factor)
Also found in: Acronyms.
BPTFA gene on chromosome 17q24.3 that encodes a histone-binding component of nucleosome-remodelling factor (NURF), a protein complex which catalyses ATP-dependent nucleosome sliding and facilitates transcription.
High levels of FAC1/BPTF may be found in foetal brain and in patients with neurodegenerative diseases (e.g., Alzheimer’s disease).
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.