Brodmann areas

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Brod·mann ar·e·as

areas of the cerebral cortex mapped on the basis of cytoarchitectural patterns. See: cerebral cortex.

The German physician Korbinian Brodmann (1868-1918) was diverted from plans to enter general practice by a long convalescence during which he worked at a sanatorium for nervous diseases. After advanced studies in neurology, neuroanatomy, pathology, and psychiatry, he began an investigation of the comparative anatomy of the mammalian cortex at the Neurobiological Laboratory of the University of Berlin. Earlier workers had divided the cortex into six principal layers on the basis of their proportions of pyramidal, stellate, and fusiform cells. Using the newly developed staining technique of Nissl, Brodmann distinguished about 50 zones of the cortex on the basis of subtle differences in cell type, size, density, and lamination, and correlated his anatomic findings with studies on localization of function in humans, subhuman primates, and other mammals. His cortical map and numbering system, published in 1909, became standard methods for distinguishing areas of cortex, and are still widely used by clinical neurologists and neurosurgeons. Although later workers have published revisions of his work, subdivided his areas, and substituted letters for his numbers, modern experimental methods have largely vindicated his cortical localizations, both anatomic and functional. see also figure at cerebral cortex.

Farlex Partner Medical Dictionary © Farlex 2012

Brod·mann ar·e·as

(brōd'mahn ar'ē-ăz)
Regions of the cerebral cortex distinguished on the basis of histologic differences and presumed differences in function.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

Brodmann areas

(brōd′man″)
[Korbinian Brodmann, Ger. neurologist, 1868–1918]
The division of the cerebral cortex into 47 areas. This was originally done on the basis of cytoarchitectural characteristics, but the areas are now classified according to their functions.
Medical Dictionary, © 2009 Farlex and Partners

Brodmann,

Korbinian, German neurologist, 1868-1918.
Brodmann area 41 - Synonym(s): primary auditory cortex
Brodmann area 44 - Synonym(s): Broca center
Brodmann areas - areas of cerebral cortex mapped out on the basis of cortical cytoarchitectural patterns.
Medical Eponyms © Farlex 2012
References in periodicals archive ?
In contrast, peak activation for lies to consistent items appeared in the left anterior cingulate region (Brodmann Area 32).
reported that delusions in patients with DLB are associated with elevated M1 binding in Brodmann area 36 [12].
Musical structure is processed in "language" areas of the brain: a possible role for Brodmann Area 47 in temporal coherence.
For instance, decreased MnSOD activity and increased 8-hydroxy-2'-deoxyguanosine, a marker of oxidatively modified DNA, were identified in Brodmann area 21 within the temporal lobe of autistic subjects [31].
Furthermore, in the workers studied, there was the possibility that afferences with the pre-central area--specifically Brodmann area 8, responsible for coordination of ocular movement- were involved (Roman Lapuente, 2010).
In addition, gray-matter volume in the subgenual anterior cingulate (Brodmann area 24) is hypoplastic in depressed persons, (16) making that area a target for deep-brain stimulation (DBS).
Compared with sham acupuncture, acupuncture at Waiguan in stroke patients inhibited Brodmann area 5 on the healthy side.
A comparison of the respective activation maps, however, revealed comprehension of affective prosody to be bound to a distinct right-hemisphere pattern of activation, encompassing posterior superior temporal sulcus (Brodmann Area (BA) 22), dorsolateral (BA 44/45), and orbitobasal (BA 47) frontal areas.
Regional fMRI activations were extracted for the following bilateral motor-sensory regions of interest (ROI): (1) primary motor region (M1, Brodmann area (BA) 4); (2) primary sensory region (S1, BA 3); (3) lateral premotor area (LPM); (4) supplementary motor area (SMA) proper (medial portion BA 6 that is posterior to the anterior commissure line) [31]; (5) thalamus; (6) cerebellum.
Activations found in the Regions of Interest in the geographical word naming VFT with phonological restriction ROI BA t (a) p (FWE-cor) Talairach Coordinates x y Z Parahippocampal Gyrus 5.32 .039 -19 -46 -11 Posterior Cingulate 31 4.50 .016 -6 -63 12 Cortex 30 4.00 .036 -6 -57 9 Lingual Gyrus 18 5.63 .003 -6 -63 5 19 4.84 .012 -10 -57 2 Left Medial Frontal 46 4.32 .041 -44 28 21 Gyrus Notes: p (FWE-cor) = p value with Family Wise Error correction; BA = Brodmann area. (a) t = One-sample t-test, degrees of freedom (df) = 15.
X coor Y coor Z coor t P 20.0 1.0 51.0 4.613.314 0.000004 Right cerebrum 5.0 61.0 12.0 6.094.687 0.000000 Right cerebrum X coor Location 20.0 Frontal lobe Subgyral Gray matter Brodmann area 6 5.0 Frontal lobe Medial Gray matter Brodmann area 10 frontal gyrus
In the context of FTLD, as well as Alzheimer disease or Lewy body dementia, a sample from the right frontal lobe (Brodmann area 9) should be obtained.