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A chelating agent, developed as an antidote for lewisite and other arsenical poisons. It acts by competing for the metal with the essential -SH groups in the pyruvate oxidase system of the cells and forms, with arsenic, a stable, relatively nontoxic cyclic compound, the metal having a greater affinity for it than for the -SH groups of the cell proteins; also used as an antidote for antimony, bismuth, chromium, mercury, gold, and nickel.
British anti-lewisite(ăn′tē-lo͞o′ĭ-sīt′, ăn′tī-)
n. Abbr. BAL
Brit·ish an·ti-Lew·is·ite(BAL) (brit'ish an'tē-lū'is-īt)
A chelating agent used in heavy-metal poisoning and against the chemical-warfare agent Lewisite.