British anti-lewisite


Also found in: Dictionary, Acronyms, Encyclopedia.

di·mer·cap·rol

(dī'mĕr-kap'rol),
A chelating agent, developed as an antidote for lewisite and other arsenical poisons. It acts by competing for the metal with the essential -SH groups in the pyruvate oxidase system of the cells and forms, with arsenic, a stable, relatively nontoxic cyclic compound, the metal having a greater affinity for it than for the -SH groups of the cell proteins; also used as an antidote for antimony, bismuth, chromium, mercury, gold, and nickel.
Synonym(s): antilewisite, British anti-Lewisite

British anti-lewisite

(ăn′tē-lo͞o′ĭ-sīt′, ăn′tī-)
n. Abbr. BAL
See dimercaprol.
A sulfhydryl compound developed in World War II as an antidote to vesicant arsenical war gases which may be used as a therapeutic chelator for arsenic, lead, mercury—inorganic mercury, but not alkylmercury or phenyl mercury—and other metal poisonings; it was formerly used for chelating copper in patients with Wilson’s disease

Brit·ish an·ti-Lew·is·ite

(BAL) (brit'ish an'tē-lū'is-īt)
A chelating agent used in heavy-metal poisoning and against the chemical-warfare agent Lewisite.
Mentioned in ?
References in periodicals archive ?
Oxidative stress also may be reduced by chelation therapy with agents such as calcium disodium ethylene diamine tetra-acetic acid (CaNa2EDTA), British anti-Lewisite (BAL), sodium 2,3-dimercaptopropane 1-sulfonate (DMPS), and meso 2,3-dimercapto-succinc acid (DMSA).
Interaction between electromagnetic radiation and toxic metals

Medical browser ?
Full browser ?