dimercaprol(redirected from British anti lewisite)
Also found in: Dictionary, Encyclopedia.
a colorless, liquid chelating agent used in the treatment of heavy metal poisoning; it forms a relatively stable compound with arsenic, mercury, gold, and certain other metals, thus protecting the vital enzyme systems of the cells against the effects of the metals. It is sometimes diluted with water and used to wash the stomach, with some of the solution being left in the stomach. Side effects include tachycardia, hypertension, nausea and vomiting, severe headaches, and a sense of constriction of the chest; barbiturates are usually ordered to relieve the symptoms, which should subside within an hour. Dimercaprol has a disagreeable skunklike odor and should be handled carefully to avoid spilling. Called also British antilewisite.
A chelating agent, developed as an antidote for lewisite and other arsenical poisons. It acts by competing for the metal with the essential -SH groups in the pyruvate oxidase system of the cells and forms, with arsenic, a stable, relatively nontoxic cyclic compound, the metal having a greater affinity for it than for the -SH groups of the cell proteins; also used as an antidote for antimony, bismuth, chromium, mercury, gold, and nickel.
A colorless oily viscous liquid, C3H8OS2, used as an antidote for poisoning caused by lewisite, organic arsenic compounds, and heavy metals including mercury and gold. Also called British anti-lewisite.
A chelating agent, developed as an antidote for lewisite and other arsenical poisons; also used as an antidote for antimony, bismuth, chromium, mercury, gold, and nickel poisoning.
dimercaprolBritish Anti-Lewisite (BAL). A drug that takes up toxic metal ions from the body and can be life-saving in poisoning with lead, arsenic, gold, mercury, antimony, bismuth and thallium. The drug is on the WHO official list. It was developed during World War I in the course of a search for antidotes to poison war gases, particularly the arsenical Lewisite.
A chemical agent used to remove excess lead from the body.
Mentioned in: Lead Poisoning