brain natriuretic peptide

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Related to brain natriuretic peptide: Atrial natriuretic peptide, troponin, C-type natriuretic peptide

brain natriuretic peptide

An atrial natriuretic peptide-like brain peptide produced predominantly in the cerebral ventricles, which induces diuresis and is secreted in response to fluid overload, as occurs in congestive heart failure.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


(pep'tid?) [ pept(ic) + -ide]
A compound containing two or more linked amino acids.

atrial natriuretic peptide

Abbreviation: ANP
Atrial natriuretic factor.

brain natriuretic peptide

B-type natriuretic peptide.

B-type natriuretic peptide

Abbreviation: BNP
A hormone secreted by the left or right ventricle of the heart Concentration of this peptide in the bloodstream rises during episodes of decompensated heart failure.
See: brain natriuretic peptide

cell-penetrating peptide

A peptide that readily crosses cell membranes and therefore can influence cellular functions or carry other molecules that can directly or indirectly perform the same tasks.

endogenous opioid peptide

Any of a group of more than 15 substances present in the brain, certain endocrine glands, and the gastrointestinal tract. They have morphine-like analgesic properties, behavioral effects, and neurotransmitter and neuromodulator functions. Included in this group of chemicals are endorphins, enkephalins, and dynorphin.

glucose-dependent insulinotropic peptide

A hormone released by cells in the upper gastrointestinal tract in response to sugary or fatty meals. It stimulates beta cells in the pancreas to secrete insulin.

immunodominant peptide

Any of the peptides having a strong affinity for binding with class I or II histocompatibility antigens and for stimulating a response by T lymphocytes. Immunodominant peptides are produced by antigen processing, are expressed on the surface of macrophages and other antigen-presenting cells, and may be useful both in desensitizing people to allergens and in vaccine production.
Synonym: immunodominant epitope

natriuretic peptide

Any peptide that stimulates the kidneys to excrete salt and water.

peptide YY

An appetite-regulating protein released by L cells of the mucosa of the gastrointestinal tract in response to a meal. It binds to cells in the arcuate nucleus of the brain, decreases the desire to eat, and creates a feeling of fullness.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
From statistical significance to clinical relevance: A simple algorithm to integrate brain natriuretic peptide and the Seattle Heart Failure Model for risk stratification in heart failure.
Frampton, "Renal, endocrine, and hemodynamic effects of human brain natriuretic peptide in normal man," The Journal of Clinical Endocrinology and Metabolism, vol.
In vivo metabolism of brain natriuretic peptide in the rat involves endopeptidase 24.11 and angiotensin converting enzyme.
Fraser, "Reduced myocardial velocities of left ventricular long-axis contraction identify both systolic and diastolic heart failure-a comparison with brain natriuretic peptide," European Journal of Heart Failure, vol.
The relation between brain natriuretic peptide and PDA diameter was determined using Pearson correlation coefficient.
The presence of brain natriuretic peptide of 12,000 daltons in porcine heart.
The utility of natriuretic peptides (NPs)--both brain natriuretic peptide (BNP) and N-terminal prohormone brain natriuretic peptide (NT-proBNP)--as an aid in diagnosing congestive heart failure (CHF) is well known.
The primary objective of this study was to determine the pattern of N-Terminal pro brain natriuretic peptide (NT-pro BNP) secretion pre and post cardiac surgery and then to investigate the correlation between levels of serum NT-pro BNP and postoperative clinical and biochemical endpoints.
Evaluation of brain natriuretic peptide as marker of left ventricular dysfunction and hypertrophy in the population.
Treatment of heart failure guided by plasma aminoterminal brain natriuretic peptide (N-BNP) concentrations.