Bowen disease


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Bow·en dis·ease

(bō'wĕn),
a form of intraepidermal carcinoma characterized by the development of slowly enlarging pinkish or brownish papules or eroded plaques covered with a thickened horny layer; microscopically, there is dyskeratosis with large round epidermal cells with large nuclei and pale-staining cytoplasm which are scattered through all levels of the epidermis.

Bow·en dis·ease

(bō'ĕn di-zēz')
A form of intraepidermal carcinoma characterized by the development of slowly enlarging pinkish or brownish papules or eroded plaques covered with a thickened horny layer; microscopically, there is dyskeratosis with large round epidermal cells with large nuclei and pale-staining cytoplasm that are scattered through all levels of the epidermis. Primary treatment includes curettage and electrodesiccation.

Bowen,

John T., U.S. dermatologist, 1857-1941.
Bowen disease - a form of intraepidermal carcinoma. Synonym(s): Bowen precancerous dermatosis
bowenoid cells - cells characteristic of Bowen disease.
bowenoid papulosis - a clinically benign form of intraepithelial neoplasia that microscopically resembles Bowen disease or carcinoma in situ, occurring in young individuals of both sexes on the genital or perianal skin usually as multiple well-demarcated pigmented warty papules.
Bowen precancerous dermatosis - Synonym(s): Bowen disease

Bow·en dis·ease

(bō'ĕn di-zēz')
A form of intraepidermal carcinoma characterized by the development of slowly enlarging pinkish or brownish papules or eroded plaques covered with a thickened horny layer.
References in periodicals archive ?
Indeed, the new guidelines rate the quality of data supporting PDT as first-line therapy for actinic keratoses, Bowen disease, and superficial BCCs as level IA--the highest-possible grade of evidence, requiring at least one well-designed, randomized, controlled trial, he noted at a satellite symposium held in conjunction with the 11th World Congress on Cancers of the Skin, cosponsored by the Skin Cancer Foundation and Erasmus University.
He said that he personally finds PDT particularly useful for treatment of large, superficial BCCs and Bowen disease.
10 reported a case where Bowen disease and small cell lung cancer were diagnosed as a cause of treatment with herbal medicine, which contained high levels of arsenic.
Basal cell carcinoma Infiltrative, morpheaform, or micronodular histologic subtype Invasion into deep subcutaneous fat, muscle, or cartilage Perineural invasion Positivity of surgical margins Presence of scar within the tumor Squamous cell carcinoma Adenoid, basaloid, small cell or spindle cell histologic subtypes Posttraumatic clinicopathologic subtype Extensive perineural, lymphatic, or vascular invasion Invasion into subcutis Positivity of surgical margins Acantholytic subtype Merkel cell carcinoma Gross size [is greater than] 2 cm Mitotic activity (10 division figures/10 high-power [x400] microscopic fields) Extensive lymphatic or vascular invasion Presence of associated Bowen disease Divergent squamous differentiation in invasive tumor Positivity of surgical margins
2 Pagetoid dyskeratosis - - - - + - Extramammary Paget disease + + + - + + Epidermotropic carcinoma + + + - + + Pagetoid Bowen disease - - - - + - Pagetoid melanoma - - - + - - 34[Beta]E12 CEA HPV HMB-45 Pagetoid dyskeratosis + - - - Extramammary Paget disease - + - - Epidermotropic carcinoma - + - - Pagetoid Bowen disease + - ND - Pagetoid melanoma - - - + (*) PAS indicates periodic-acid Schiff; AB, Alcian blue at pH 2.