inflammatory bowel disease(redirected from Bowel inflammation)
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inflammatory bowel disease
any of various inflammatory diseases of the bowel whose etiology is unknown, including crohn's disease and ulcerative colitis.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
inflammatory bowel disease (IBD),
general term for Crohn disease and ulcerative colitis, chronic disorders of the small and large intestine, of unknown cause, with conspicuous inflammatory features and distinctive but overlapping signs and symptoms.
Farlex Partner Medical Dictionary © Farlex 2012
inflammatory bowel disease
n. Abbr. IBD
Any of several chronic disorders of the gastrointestinal tract, especially Crohn's disease and ulcerative colitis, characterized by inflammation and ulceration of the intestine and resulting in abdominal cramping and diarrhea.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
inflammatory bowel diseaseA general term for the symptoms associated with specific types of inflammation of the large intestine, including Crohn's disease–CD, ulcerative colitis–UC as well as idiopathic inflammatory bowel disease, a diagnosis of exclusion that clinically and pathologically mimics and/or overlaps CD and UC Heredity First-degree relatives of Pts with CD and UC have an 8- to 10-fold ↑ risk of developing the same form of colitis DiffDx Ischemia, radiation, uremia, cytotoxic drugs, heavy metal intoxication; IBD Pts often have ≥ 2 of following: Visible abdominal distension, relief of pain upon defecation, looser and more frequent bowel movements when the pain occurs; ♂:♀ ratio, 2:1; more common in Jews; IBD is associated with mucocutaneous disease–pyoderma gangrenosa, erythema nodosum, oral ulcers, annular erythema, vascular thromboses, epidermolysis bullosa, ocular disease–uveitis, iridocyclitis, hepatopathy–CAH, cirrhosis, sclerosing cholangitis, arthropathy–ankylosing spondylitis. Cf Irritable bowel syndrome Treatment Corticosteroids—or corticotropin–favored by some clinicians, aminosalicylates–sulfasalazine and 5-aminosalicylic acid, immunomodulatory agents–azathioprine, mercaptopurine, cyclosporine, MTX, metronidazole, antibiotics and nutritional support–both more effective in Crohn's disease, resulting in ↓ Sx, ↓ inflammatory sequelae, improved nutritional status.
Inflammatory bowel disease
Clinical Ulcerative colitis Crohn's disease
Rectal bleeding Common Rare
Abdominal mass Rare 10-15%
Abdominal pain Left-sided Right-sided
Abnormal endoscopy 95% < 50%
Perforation 12% 4%
Colon carcinoma 5-10% Rare
Response to steroids 75% 25%
Surgical outcome Excellent Fair
Rectal involvement > 95% !0%
Ileal involvement Rare Usual
Cross-hatched ulcers Rare Occasional
Thumbprinting Absent Common
Fissuring Absent Common
Skip areas Absent Common
Strictures Absent Common
Distribution Diffuse Focal
Mucosal atrophy Regeneration Marked Minimal
Hyperemia Often marked Minimal
Crypt abscess Common Rare
Cytoplasmic mucin Decreased Intact
Lymphoid aggregates Rare Common
Lymph nodes Reactive hyperplasia -----
Edema Minimal Marked
Granulomas Absent 60%
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
in·flam·ma·to·ry bow·el dis·ease(IBD) (in-flam'ă-tōr-ē bow'ĕl di-zēz')
General term for Crohn disease and ulcerative colitis, chronic disorders of the small and large intestine, autoimmune, with conspicuous inflammatory features and distinctive but overlapping signs and symptoms.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
Inflammatory bowel disease (IBD)
Ulcerative colitis or Crohn's colitis; chronic conditions characterized by periods of diarrhea, bloating, abdominal cramps, and pain, sometimes accompanied by weight loss and malnutrition because of the inability to absorb nutrients.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.