The 4 exceptions comprise 2 families that have no known human-infective viruses (Arteriviridae and Birnaviridae) and 2 with species that have been reported in humans but only at level 2 (Asfarviridae and Bornaviridae
Initially designated as ABV-CG due to the high prevalence in Canada geese, the virus has been renamed aquatic bird bornavirus 1 (ABBV-1) in a reorganization of the taxonomy of the Bornaviridae (4).
Taxonomic reorganization of the family Bornaviridae. Arch Virol.
Only recently has the cause of the disease been identified by characterization of a newly discovered member of the family Bornaviridae
, the avian bornavirus (ABV), which has been detected in affected psittacines (3,4).
Recently, 2 independent groups of investigators identified a new member of the family Bornaviridae
, named avian bornavirus (ABV), in parrots with histopathologically confirmed PDD.
(9) provided evidence that PDD is associated with the presence of novel virus species within the family Bornaviridae
, provisionally termed avian bornavirus (ABV).
As the prototype and only known member of the family Bornaviridae
in the order Mononegavirales (nonsegmented, negative-strand RNA viruses), BDV is atypical in its nuclear localization of transcription, alternative splicing, and differential use of initiation and termination signals.
Borna disease (BD) is a severe immunopathologic disorder of the central nervous system induced by infection with Borna disease virus (BDV), the prototype of a new virus family, Bornaviridae
, within the order Mononegavirales.