Borna disease

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Related to Borna virus: encephalitis

Borna disease

An infectious encephalopathy of warm-blooded animals, including ruminants (e.g., cattle, horses, sheep), foxes, dogs, cats, birds and primates, which occurs in Central Europe, caused by the Borna virus.
 
Clinical findings
Motor and behavioural symptoms—aggression, eating disorders, hyperactivity, postural disorders, ataxia, disrupted social and sexual activity.
 
Epidemiology
Uncertain, probably via saliva or nasal secretions.

Mortality
Up to 100% in horses, 50% in sheep.
References in periodicals archive ?
Depression is a very complex illness, involving among other things genetic factors and stress, to which the Borna virus has now been added as another probable player.
Bode and his colleagues obtained the Borna virus from three people who had been diagnosed with mood disorders.
Earlier studies showed that the Borna virus has evolved over eons into distinct strains, each with a predilection for a specific animal species.
Furthermore, Borna virus antibodies have been reported in nearly one-third of people with certain mental illnesses, including obsessive-compulsive disorder and schizophrenia, he says.
The diagnosis of proventricular dilatation disease: use of a Western blot assay to detect antibodies against avian borna virus. Vet Microbiol.
Behavioral disease in rats caused by immunopathological responses to persistent borna virus in the brain.