Borna disease virus

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Bor·na dis·ease vi·rus

an unclassified negative sense single-stranded RNA virus that is the cause of Borna disease, a serious disease of horses that involves infection of the central nervous system.
[Borna, Saxony, Germany]


A small nonsegmented, negative-sense, single-stranded RNA virus, which infects a broad range of warm-blooded animals and is capable of replicating within the host nuclus.
References in periodicals archive ?
Detection of Borna disease virus RNA in formalin-fixed, paraffin-embedded brain tissues by nested PCR.
Distribution of Borna disease virus in the brain of rats infected with an obesity-inducing virus strain.
Restricted expression of Borna disease virus glycoprotein in brains of experimentally infected Lewis rats.
Genetic clustering of Borna disease virus natural animal isolates, laboratory and vaccine strains strongly reflects their regional geographical origin.
Borna disease virus, a negative-strand RNA virus, transcribes in the nucleus of infected cells.
Molecular basis for the different subcellular localization of the 38-and 39-kilodalton structural proteins of Borna disease virus.
Nuclear targeting activity associated with the amino terminal region of the Borna disease virus nucleoprotein.
Atypical dissemination of the highly neurotropic Borna disease virus during persistent infection in cyclosporine A-treated, immunosuppressed rats.
The immunopathogenesis of Borna disease virus infection.
Rat model of Borna disease virus transmission: epidemiological implications.
double dagger]) The calibrated values were calculated by using the sum of both normalized Ct-values of Borna disease virus p24 and p40, respectively, and dividing it by the normalized value of the 18s rRNA (5).