Significant finding of Bordetella holmesii DNA in nasopharyngeal samples from French patients with suspected pertussis.
Epidemiologic and laboratory features of a large outbreak of pertussis-like illnesses associated with cocirculating Bordetella holmesii and Bordetella pertussis--Ohio, 2010-2011.
Real-time PCR assay targeting IS481 of Bordetella pertussis and molecular basis for detecting
Bordetella holmesii.
A false-positive result for Bordetella pertussis DNA may occur if
Bordetella holmesii is present in the sample; however,
Bordetella holmesii is found at a much lower prevalence than Bordetella pertussis.
pertussis and
Bordetella holmesii and may be present in Bordetella bronchiseptica (6-10) (see Table 1 in the Data Supplement that accompanies the online version of this Technical Brief at http://www.
22) The TaqMan primers and probes presented in this study also exhibit cross-reactivity with
Bordetella holmesii but fail to produce amplicon from B parapertussis, Bordetella bronchispetica, Haemophilus influenza, Moraxilla catarrhalis, Legionella pneumophila, or Streptococcus pneumoniae in high input as anticipated (E.
To the Editor: We report a case of recurrent
Bordetella holmesii bacteremia with 4 clinical manifestations: 3 episodes of cellulitis and 1 episode of pneumonia.
PCR testing yielded two specimens with results consistent with
Bordetella holmesii.
On the basis of bacterial 16S rRNA gene sequence analysis, an emerging pathogen,
Bordetella holmesii, has been successfully identified in the immunocompromised hosts [130, 131].
Subsequent biochemical analysis, 16S rRNA sequencing, and DNA relatedness studies revealed that these strains were new Bordetella species, which was named
Bordetella holmesii to honor Barry Holmes (10).
We describe the epidemiology of a pertussis outbreak in Japan in 2010-2011 and
Bordetella holmesii transmission.
We isolated
Bordetella holmesii, generally associated with septicemia in patients with underlying conditions, from nasopharyngeal specimens of otherwise healthy young persons with a cough.
