To the Editor: We report a case of recurrent Bordetella holmesii bacteremia with 4 clinical manifestations: 3 episodes of cellulitis and 1 episode of pneumonia.
Significant finding of Bordetella holmesii DNA in nasopharyngeal samples from French patients with suspected pertussis.
A false-positive result for Bordetella pertussis DNA may occur if Bordetella holmesii
is present in the sample; however, Bordetella holmesii
is found at a much lower prevalence than Bordetella pertussis.
pertussis and Bordetella holmesii and may be present in Bordetella bronchiseptica (6-10) (see Table 1 in the Data Supplement that accompanies the online version of this Technical Brief at http://www.
Real-time PCR assay targeting IS481 of Bordetella pertussis and molecular basis for detecting Bordetella holmesii.
22) The TaqMan primers and probes presented in this study also exhibit cross-reactivity with Bordetella holmesii
but fail to produce amplicon from B parapertussis, Bordetella bronchispetica, Haemophilus influenza, Moraxilla catarrhalis, Legionella pneumophila, or Streptococcus pneumoniae in high input as anticipated (E.
Subsequent biochemical analysis, 16S rRNA sequencing, and DNA relatedness studies revealed that these strains were new Bordetella species, which was named Bordetella holmesii to honor Barry Holmes (10).
Bordetella holmesii in nasopharyngeal samples from Chilean patients with suspected Bordetella pertussis infection.
On the basis of bacterial 16S rRNA gene sequence analysis, an emerging pathogen, Bordetella holmesii
, has been successfully identified in the immunocompromised hosts [130, 131].
We describe the epidemiology of a pertussis outbreak in Japan in 2010-2011 and Bordetella holmesii transmission.
Bordetella holmesii, a small gram-negative coccoid bacillus that was first reported in 1995 (7), was originally identified as a member of the Centers for Disease Control and Prevention nonoxidizer group 2.
We isolated Bordetella holmesii
, generally associated with septicemia in patients with underlying conditions, from nasopharyngeal specimens of otherwise healthy young persons with a cough.