Bordetella pertussis

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Bor·de·tel·la per·tus·'sis

the bacterial species that is the causative agent of whooping cough, a respiratory tract infection that in infants and young children may be life threatening; the severe cough, progressing to a paroxysmal form after 7-10 days, is associated with production of pertussis toxin, a protein consisting of 5 B. subunits that bind the molecule to respiratory epithelial cells, and an A subunit, an ADP-ribosyl-transferase that interferes with proteins associated with normal signal transduction; pathology is also associated with heavy secretion of mucus and hypoxia due to paroxysmal coughing and to blockage of air passages with mucus.

Bordetella pertussis

A small, aerobic, gram-negative bacillus, which classically causes whooping cough. B pertussis produces various toxins including a dermo-necrotising toxin, an adenyl cyclase, an endotoxin and pertussis toxin, as well as surface components such as fimbrial haemagglutinin.

Clinical findings
Runny nose, sneezing, mild cough, low-grade fever.
 
Diagnosis
Culture, serology.

Bordetella pertussis

Microbiology A small, aerobic, gram-negative bacillus, causative organism of whooping cough; B pertussis produces various toxins including a dermonecrotizing toxin, an adenyl cyclase, an endotoxin and pertussis toxin, as well as surface components such as fimbrial hemagglutinin Diagnosis Culture, serology, clinical Rx

Bor·de·tel·la per·tus·sis

(bōr-dĕ-tel'ă pĕr-tŭs'is)
A bacterial species that causes whooping cough; it produces cell-destroying toxins and causes thick mucus to collect in the airway. The type species of the Bordetella genus.

Bor·de·tel·la per·tus·sis

(bōr-dĕ-tel'ă pĕr-tŭs'is)
A bacterial species that causes whoo-ping cough.

Bordetella

a genus of gram-negative bacteria which cause respiratory disease in a number of species.

Bordetella avium
the cause of turkey coryza. Previously called Alcaligenes fecalis.
Bordetella bronchiseptica
a small, gram-negative, motile bacillus. A normal inhabitant of the respiratory tract in humans, dogs and pigs, but also causes pneumonia, stillbirths, abortions, canine infectious tracheobronchitis (see kennel cough) and atrophic rhinitis in pigs.
Bordetella parapertussis
implicated in pneumonia in sheep, in association with Mannheimia haemolytica.
Bordetella pertussis
the cause of whooping cough in humans. Used as an adjuvant for immunostimulation.