osteocalcin

(redirected from Bone GLA Protein)
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Related to Bone GLA Protein: matrix Gla protein, BGLAP

os·te·o·cal·cin

(os'tē-ō-kal'sin),
A protein found in osteoblasts and dentin; contains γ-carboxyglutamyl residues; has a role in mineralization and calcium ion homeostasis.
Synonym(s): bone Gla protein

osteocalcin

(ŏs′tē-ō-kăl′sĭn)
n.
A calcium-binding substance produced by osteoblasts that is essential to bone mineralization and can be used as a biomarker for osteoporosis. It may also act as a hormone to increase insulin production and insulin sensitivity.

osteocalcin

[-kal′sin]
a protein found in the extracellular matrix of bone and dentin and involved in regulating mineralization in the bones and teeth.

BGLAP

A gene on chromosome 1q25-q31 that encodes a protein which constitutes 1–2% of bone protein, which binds strongly to apatite and calcium.

os·te·o·cal·cin

(os'tē-ō-kal'sin)
Protein found in osteoblasts and dentin.

osteocalcin (os´tēōkal´sin),

n vitamin Kdependent calcium-binding protein synthesized by osteoblasts and found primarily in bone. Serum osteocalcin measurements provide a noninvasive specific marker of bone metabolism.

osteocalcin

a product of the resorption of bone.
References in periodicals archive ?
Determination of bone Gla protein (osteocalcin) by enzyme-linked immunosorbent assay.
Direct demonstration that the vitamin K-dependent bone Gla protein is incompletely [gamma]-carboxylated in humans.
Serum bone GLA protein compared to bone histomorphometry in endocrine diseases.
Osteocalcin or bone Gla protein (BGP) is a vitamin K-dependent, low-molecular-mass (5800 Da), 49 amino acid peptide synthesized by osteoblasts [1, 2].