Bombay blood type | definition of Bombay blood type by Medical dictionary
Bombay blood type
Bom·bay blood type (bom-bā' blŭd tīp)
Blood type of those who possess the genes for A and B antigens but are unable to express the genes because they lack the gene for H antigen, a required precursor of A and B. People with this blood type frequently have anti-H in their blood.
Fig. 76 Bombay blood type . (a) Normal and (b) Bombay blood group types.
Bombay blood type a rare blood type in which individuals appear to be Group O (see ABO BLOOD GROUP) and yet can produce offspring of a type normally impossible for a Group O parent. It appears that Bombay types are homozygous (see HOMOZYGOTE) for a pair of recessive h alleles that inactivates the production of the ABO blood group antigen, even though they have the genes to manufacture these antigens, a form of EPISTASIS.
References in periodicals archive
A family of Bombay blood type
with suppression of blood group substance A1.