A, An amelanotic small round blue cell tumor
is present beneath denuded surface epithelium.
She underwent enucleation of the cyst and histopathological examination revealed a high grade small round blue cell tumor
with features suggestive of EES [Figure 1a].
Each 1 (0.7%) case of round blue cell tumor
and metastatic papillary thyroid carcinoma were also seen in this study.
MCC is "a small round blue cell tumor
" and must be differentiated from metastatic visceral neuroendocrine carcinomas, particularly from small cell lung carcinoma (SCLC) or other small round cell tumors .
Pathology revealed a small round blue cell tumor
positive for CD99/MIC-2 antigen suggestive of Ewing's sarcoma.
Ultrasound-guided biopsy showed a small round blue cell tumor
. Immunohistochemistry showed strong membranous positivity with CD99 and some positivity with CD56 and synaptophysin.
Rashad, "Potential therapeutic genomic alterations in desmoplastic small round blue cell tumor
," Journal of Clinical Oncology, vol.
Caption: Figure 2: Diffusely infiltrative small blue cell tumor
, magnification (100x); round cells with scant cytoplasm and moderate degree of nuclear atypia, magnification (200x).
Primitive Neuro Ectodermal Tumor (PNET) is a malignant small round blue cell tumor
exhibiting a variable degree of neural differentiation, which arises outside the brain, spinal cord and sympathetic nervous system.
On low power, melanotic neuroectodermal tumor of infancy resembles a small round blue cell tumor
, in this case consisting of sheets of cells in a fibrocollagenous stroma (hematoxylin-eosin, original magnification X100).
3).Based on above findings, a cytologic diagnosis of a small round blue cell tumor
was given and we requested a USG-guided biopsy for classification and subtyping of tumor.
A review of literature, reveals several cases of pilomatrixoma misinterpreted as trichilemmal cyst, epidermal inclusion cyst, granulomatous lesions, squamous and basal cell carcinoma, lymphomas, small round blue cell tumor
, salivary gland and other appendageal tumors.