The lesions start as pink or skin-colored asymptomatic papules in a linear orientation following the lines of Blaschko
. Lesions usually evolve over several weeks, and typically resolve in 6-12 months.
"Pruritic, Purple, Polygonal, Planar, Papules and Plaques" are the traditional 6 "P's" of LP.7 Annular lesions are especially common on the penis and rarely may be the predominant type of lesion present, later leading to atrophy.8 When the palms and soles are affected, the lesions tend to be firm and rough with a yellowish hue.9 Linear LP occurring in Blaschko
's lines can also be observed.10 Mucous membrane lesions are very common, occurring in 30-70% of cases.
Physical examination revealed streaks and whorls of hyperpigmented macules along the lines of Blaschko
, located on the trunk and limbs [Figure 1].
(16.) Yang G, Zaid UB, Erickson BA, Blaschko
SD, Carroll PR, Breyer BN.
Linear atrophoderma of Moulin (LAM) is an acquired condition that presents with unilateral, depressed plaques following Blaschko
's lines (3).
Lichen striatus (LS) is an uncommon linear dermatosis that most commonly affects children aged 4 months to 15 years and is distributed along the lines of Blaschko
. Diagnosis is made based on clinical appearance of 2 to 4 mm, flat-topped, lichenoid papules ranging from red color to flesh color that are distributed linearly and may be discrete or confluent [1, 2].
Hypomelanosis of Ito, described in 1952 as incontinentia pigmenti achromians, is a rare neuroectodermal disorder characterized by mainly hypopigmented and in some cases hyperpigmented anomalies following the Blaschko
lines associated with neurological, ocular, and musculoskeletal abnormalities.
* This differs from Blaschko
lines, which form a specific surface pattern that is believed to reflect the migration of embryonic skin cells.
, S.D., McCulloch, C.E., McAnich, J.W., & Breyer, B.N.
, "Bond Behavior of Strips Glued into Slits," in FRPRCS-6, pp.
, "Learning a category independent object detection cascade," in Proc.
Stage 3 is characterized by the presence of linear or swirl pigmentations, grey/greybrownish, parallel to Blaschko
lines, frequently localized on the torso and the base of members.