bisphenol A

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bisphenol A

(bĭs-fēn′ŏl) [L. bis, twice + ″],

BPA

A chemical used in many consumer products to increase their durability and toughness. Its chemical formula is 2,2–bis (4,4′-hydroxyphenyl) propane. It is used principally in manufacturing polycarbonates and epoxy resins. It has estrogen-like effects in animal tissue. Some studies have suggested that BPA has negative hormonal effects on adults and the developing fetus.
References in periodicals archive ?
But, she pointed out, the replacement chemicals are structurally similar to BPA -- as implied by names like bisphenol S and bisphenol F, two of the most common BPA substitutes.
NTP-CERHR monograph on the potential human reproductive and developmental effects of bisphenol A.
The committee is also to advise the Federal Government on the resolution of the House of Rep to ban the use of Bisphenol -A (BPA), plastics in the production of bottled water in the country
However, she and her colleagues were able to determine that the mice were being exposed to replacement bisphenols. They also saw that the disturbance in the lab was causing problems in the production of both eggs and sperm.
The fluorinated bisphenol analogue, Bisphenol AF (BPAF), was nominated for health effects assessment by the National Toxicology Program (NTP) in 2008 because estrogenic activity assays reported that BPAF (53.4 nM) is an agonist and binds to estrogen receptor alpha (ER[alpha]) with ~20x greater affinity than BPA (1030 nM), and BPAF is a full antagonist for ER[beta] (Kitamura et al.
Maternal, placental and fetal exposure to bisphenol A in women with and without preeclampsia.
Surprisingly enough, despite increase in expression of BPA concentration (25 and 125 [micro]g), the increased expression was not dependent on increased bisphenol A condensation; so gene expression was decreased at every level compared to previous level; and, contrary to GADD45B gene expression, the difference was not further significant at the concentration of 125 [micro]g of bisphenol A compared to the control group (Figure 3).
Bisphenol S and F: a systematic review and comparison of the hormonal activity of bisphenol A substitutes.
The key players in the Bisphenol A market include, Bayer Material Science, Dow Chemical, LG Chemical, Kumho P&B Chemicals, Mitsui Chemicals, SABIC Innovative Plastics, Formosa Plastics, Samyang Innochem, Teijin and Vinmar International.
Bisphenol A is one of the most thoroughly studied chemical substances and for decades has been used for the production of the high-performance plastic polycarbonate, among other things.
Bisphenol S has the same toxic, hormone-disrupting effects in cells and in animals as its relative bisphenol A.
Bisphenol A (BPA) is an organic compound classified to the group of phenols.