bioassay

(redirected from Bioassays)
Also found in: Dictionary, Thesaurus, Encyclopedia.

bioassay

 [bi″o-as´a]
determination of the active power of a drug sample by comparing its effects on a live animal or an isolated organ preparation with those of a reference standard.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

bi·o·as·say

(bī'ō-as'ā),
Determination of the potency or concentration of a compound by its effect on animals, isolated tissues, or microorganisms, as compared with an analysis of its chemical or physical properties.
Farlex Partner Medical Dictionary © Farlex 2012

bioassay

(bī′ō-ăs′ā′, -ă-sā′)
n.
1. Determination of the strength or biological activity of a substance, such as a drug, by comparing its effects with those of a standard preparation on a test organism.
2. A test used to determine such strength or activity.
tr.v. bioas·sayed, bioas·saying, bioas·says
To cause to undergo a bioassay.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

bioassay

Lab medicine
Any quantification procedure to detect:
(1) The activity or potency—functional or effective—amount of a substance—e.g., antibiotic, chemical, drug, hormone, metabolit, vitamin, etc.—in a biological fluid;
(2) Toxicity of a substance (e.g., a pollutant) or organism (e.g., a pathogen) of interest in an in vivo system, i.e., in a cell or animal; in bioassays, the effect is tested on living cells or organisms.
 
Molecular biology
An assay that uses a living system, such as an intact cell, to measure an effect or a molecule of interest.
 
Radiation physics
A determination of the quantity of radioactive material in the human body, either by direct measurement—in vivo counting—or by analysis of excreta.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

bi·o·as·say

(bī'ō-as'ā)
Determination of the potency or concentration of a compound by its effect on animals, isolated tissues, or microorganisms, as contrasted with analysis of its chemical or physical properties.
Synonym(s): biologic assay, biotest.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

bioassay

A method of measuring the potency of a drug or other biochemical agent by comparing its effects on animals with those of known preparations of standard strength.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
Bioassays were conducted in a completely randomized design at concentrations of 0.5%, 1.0%, 2.0%, 4.0%, and 8.0% of the leaf extract of P aduncum and acetone P.A.
Because the resistance level exceeded the threshold at which accurate [LT.sub.50] levels were obtainable, in 2013, a variation of the CDC bottle bioassays was used to calculate the strength of resistance.
In relation to the concentrations in the tested solutions of STX and neoSTX, there was a difference in the production of neoSTX between the two cultures of CYRF used in the bioassays (number 1 and remaining assays--Table 1).
White-rotting fungi usually cause lower mass losses in softwoods than brown-rotting fungi in bioassays, and this occurred with P.
An inexpensive and rapid bioassay would be a useful screening tool with which to assess potential decontaminating agents for subsequent, more definitive testing by chemical analysis.
This process has three basic steps: grinding, extraction, and bioassays for bioactivity.
Parallex BioAssays was founded in 2015 in Montreal, Canada, with a mission to offer innovative and customizable solutions to accelerate academic and industrial research.
For bioassays, the leaves with actively feeding third instar CLM larvae were collected from citrus mandarins in the field.
parahaemolyticus challenge (bioassays one and two), a bioassay (4 d) was conducted to determine the [LC.sub.50] (lethal concentration, 50%) using animals weighing 528 [+ or -] 31.7 mg and 452 [+ or -] 50 mg.