bioartificial organ

bioartificial organ

An implanted synthetic device designed to replace the function of a failing organ—e.g., liver cells housed in a synthetic hollow-fibre dialysis cartridge, allowing donor-cell contact with host fluids, while preventing donor-antigen contact with the host immune system, thereby minimising rejection.
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A continuous supply of oxygen is needed from the time that the cells are first isolated from a donor pancreas until the bioartificial organ is implanted and develops its own blood vessels, typically five to 10 days post-transplant," said Opara.
Reassessments of these immunoisolation standards are thus required before viable bioartificial organ research employing these membranes can continue.
They can be used for many biotech applications including bioartificial organ development.
Membrane Systems: For Bioartificial Organs and Regenerative Medicine
Vladimir Vasilets is head researcher at the Federal Scientific Research Centre of Transplantology and Bioartificial organs in Moscow.
When methods to cryopreserve complex tissues are perfected, it will become possible to store virtually every tissue in the body--whether taken from human donors, grown in the laboratory from stem cells, or combined with artificial components to form bioartificial organs.
Chapters discuss thermodynamic concepts, physical properties of the body fluids and the cell membrane, physical and flow properties of blood and other fluids, solute and oxygen transport in biological systems, pharmacokinetic analysis, extracorporeal devices, tissue engineering, and bioartificial organs.