A proprietary—CryoLife—adhesive used to repair aortic dissections, seal vessels, and reconstruct and reinforce peribronchial soft tissue to decrease air leaks
Composition Bovine serum albumin and glutaraldehydeare dispensed via a double-chambered syringe. Once dispensed, the adhesive components mix within the applicator tip where the cross-linking begins (within 20 to 30 seconds; it reaches bond strength within 2 minutes). The glutaraldehyde molecules bond with the BSA molecules creating a flexible mechanical seal independent of the body's clotting mechanism.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
There are many types of HAs and glues, such as gelatine matrix thrombin tissue sealant (FloSeal; Baxter Healthcare, Deerfield, IL, USA), fibrin glue (Tisseel; Baxter), bovine serum albumin-based adhesive (BioGlue; CryoLife, Keeensaw, GA, USA), and cyanoacrylate glue (Glubran; General Enterprise Marketing, Viareggio, Lucca, Italy).
Harvard University scientists have created a socalled bioglue, based on the mucus secreted by slugs which, they claim, is very strong and sticks even in very moist situations.
The increase was driven by strong revenue growth from JOTEC, On-X and BioGlue.
Cerebrospinal fluid leak rate after the use of BioGlue in translabyrinthine vestibular schwannoma surgery: a prospective study.
BioGlue (25% bovine serum albumin and 10% glutaraldehyde; Cryolife Inc., Kennesaw, GA, USA) was approved by the FDA in 1998 for surgical application and is utilized in cardiovascular and pulmonary surgery, that is, for application during aortic root reconstruction and valve placement as well as for control of alveolar air leaks [21, 22].
Treatment of splenic injury during laparoscopic nephrectomy with BioGlue, a surgical adhesive.
The abnormal diaphragmatic surface was sealed with bioglue, and a vascularized parietal pleural flap was created and tacked over the diaphragm with permanent suture (Figure 4).
CryoLife, Inc, Atlanta, GA, announced that its BioGlue Surgical Adhesive has received Shonin approval from the Japanese Ministry of Health, Labor and Welfare (MHLW) for use in the repair of aortic dissections.
With the help of micro-manipulation technique, the researchers measured the force needed to overcome the bioglue adhesion, and showed that dried biofilm stuck 20-times more tightly than fresh biofilm.