ligand

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Related to Bidentate ligand: tridentate ligand

ligand

 [li´gand, lig´and]
an organic molecule that donates the necessary electrons to form coordinate covalent bonds with metallic ions. Also, an ion or molecule that reacts to form a complex with another molecule.

lig·and

(lig'and, lī'gand),
1. Any individual atom, group, or molecule attached to a central metal ion by multiple coordinate bonds, for example, the porphyrin portion of heme, the corrin nucleus of the B12 vitamins.
2. An organic molecule attached to a tracer element, for example, a radioisotope.
3. A molecule that binds to a macromolecule, for example, a ligand binding to a receptor.
4. The analyte in competitive binding assays, such as radioimmunoassay.
5. An atom or group covalently attached to a specified carbon atom in an organic molecule.
[L. ligo, to bind]

ligand

(lī′gənd, lĭg′ənd)
n.
An ion, molecule, or molecular group that binds to another chemical entity to form a larger complex.

li·gand

(lī'gand)
1. An organic molecule attached to a central metal ion by multiple coordinate bonds.
2. An organic molecule attached to a tracer element, e.g., a radioisotope.
3. A molecule that binds to a macromolecule, e.g., a ligand binding to a receptor.
4. The analyte in competitive binding assays, such as radioimmunoassay.
[L. ligo, to bind]

ligand

A MOLECULE or ION that binds to a central chemical entity by non-covalent bonds. A general term for any molecule that is recognized by a surface receptor.

ligand

a molecule able to bind to a specific ANTIBODY and used to distinguish closely similar types of antibody.

li·gand

(lī'gand)
1. Any individual atom, group, or molecule attached to a central metal ion by multiple coordinate bonds.
2. An organic molecule attached to a tracer element.
3. A molecule that binds to a macromolecule.
[L. ligo, to bind]
References in periodicals archive ?
Coordination of the pyridylquinoline bidentate ligands to the Rh(III) source (Rh[Cl.sub.3] x 3[H.sub.2]O, I[C.sub.50] = 67 [micro]M) improves slightly the biological profile of the metal-based inhibitors, although the Rh(III) metal precursor is not that potent inhibitor as the relevant [Re[(CO).sub.5]Cl] analogue.
Dithiolate ligands are unsaturated bidentate ligands and react with transition metals to form dithiolene complexes [1, 2].
On the other hand, bidentate ligands, which cannot form this type of trans-complexes, have been successfully used in the copper-free Sonogashira reaction [39] and the reaction of cis-Pd[([PPh.sub.3]).sub.2](Ph)Br with alkyne should be considered as a possible reaction pathway.
Both TPG and glycerol have multiple -OH groups capable of forming chemical bonds with titanium and previous studies have shown that bidentate ligands are more strongly bound and less susceptible to hydrolysis.
Bidentate ligands such as 2,4- and 2,5-pyridine dicarboxylic acids have been studied and shown promising results with both Ni(II) and Co(II) salts.
Also, an extra chelation site on oxygen atom makes it a useful precursor for the synthesis of bidentate ligands [5].
The overall project has been divided into four separate phases: synthesis of the acridine derivative chosen as the intercalating moiety, synthesis of the bidentate ligands, coupling of the ligands to the acridine derivative, and chelation of the ligands with bis(bipyridyl)ruthenium(ll)dichloride.
For the purposes of this article, it is sufficient to note that anionic, cationic and neutral indium(III) complexes are known with a wide range of monodentate and bidentate ligands, and that coordination numbers between 3 and 6 have been identified.
A number of papers [14, 15] highlight the flexible nature of bidentate ligands, their analytical, and biological properties.
Kepert's treatment of coordination numbers and geometrics, especially for complexes with bidentate ligands and mixed monodentate-bidentate complexes, follows his book on the same subject, and is logically placed as the second chapter.
Ahmad, Synthesis, Characterization and Biological Evaluation of Transition Metal Complexes Derived from N, S Bidentate Ligands, Int.
The infrared spectral data exhibited that the used ligands behaving as bidentate ligands towards the metal ions.