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One should emphasize, however, that one of the four parts of the new Bethesda classification specifies such inflammatory lesions as: Trichomonas vaginalis, Candida, Actinomyces, Chlamydia, cellular changes consistent with HSV infection, and changes of bacterial flora.
Pap Smear Finding according to Bethesda Classification Diagnosis Number of Patients Percentage (%) Inadequate 35 5 NILM Normal 107 15.
The intention was to develop a system of classification of thyroid FNA similar in scope to the Bethesda Classification for gynecologic cervical cytology.
The target population includes categories III (atypia of indeterminate significance or follicular lesion of indeterminate significance (AUS / FLUS)) and IV (follicular neoplasm or suspicion of follicular neoplasm (FN / SFN)) of the Bethesda classification.
The purpose of this study was to evaluate Bethesda Classification for reporting thyroid by recording interobserver reproducibility.
Comparison of the Bethesda and the British Society for Clinical Cytology (BSCC) classification systems for cervical cytology (8) Bethesda classification BSCC classification Negative for intraepithelial lesion or malignancy Negative Unsatisfactory for evaluation Inadequate Atypical squamous cells of undetermined Borderline significance (ASC-US) nuclear change Atypical squamous cells cannot exclude H-SIL (ASC-H) Atypical endocervical, endometrial or glandular cells (not otherwise specified or specify) Atypical endocervical or glandular cells favour neoplasia Low-grade squamous intraepithelial lesion (L-SIL) Mild dyskaryosis High-grade squamous intraepithelial lesion (H-SIL) Moderate dyskaryosis Severe dyskaryosis Squamous cell carcinoma Severe dyskaryosis ?
Pap results were read in Sao Paulo using traditional classification methods, then again in Montreal using the Bethesda classification system.
In the Bethesda classification system, abnormal Paps are labeled LSIL (low-grade squamous intraepithelial lesions), HSIL (high-grade squamous intraepithelial lesions), or ASCUS (atypical squamous cells of undetermined significance).
The 510(k) application used data from a clinical trial that measured cellularity, (whether a sufficient number of cells was collected), adequacy (the presence of cells representative of the endocervix and transformation zone - the two areas of the cervix where cervical cancer typically starts), reporting according to the Bethesda Classification System, and patient comfort.
Wang et al propose a 6-tier cytopathologic classification system, similar to the Bethesda classification for thyroid fine needle aspiration, for fine-needle aspiration biopsy of salivary gland lesions.
On further analysis of Pap smear results according to Bethesda Classification, we found that inflammatory Pap results were found in 58.