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Related to Betalactam: ESBL


A class of broad-spectrum antibiotics that are structurally and pharmacologically related to the penicillins and cephalosporins.
Farlex Partner Medical Dictionary © Farlex 2012


(bā′tə-lăk′təm, bē′-)
1. A lactam composed of a four-membered ring, formed by intramolecular condensation of an amino acid in which the amino group is located at the beta position, or any compound containing this group.
2. A beta-lactam antibiotic.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.


(bā'tă lak'tam)
Class of broad-spectrum antibiotics structurally and pharmacologically related to penicillins and cephalosporins.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
Gueant-Rodriguez et al., "Allergy to betalactams and nucleotide-binding oligomerization domain (NOD) gene polymorphisms," Allergy, vol.
It results from alterations in penicillin-binding proteins, with the degree of resistance dependent on the particular proteins affected and the binding affinity of the betalactam agent used.
Betalactam susceptibilities and prevalence of ESBL-producing isolates among more than 5000 European Enterobacteriaceae isolates.
Bados-Albiero et al., "Allergy to betalactam antibiotics in children: results of a 20-year study based on clinical history, skin and challenge tests," Pediatric Allergy and Immunology, vol.
Antepara et al., "Flow cytometric basophil activation test by detection of CD63 expression in patients with immediate--type reactions to betalactam antibiotics," Clinical and Experimental Allergy, vol.
Both nafcillin and cefazolin are considered first-line options for for therapy for most MSSA infections, and recent studies suggest that the two betalactam antibiotics have similar efficacy, Dr.
It is worth recalling that Hospira signed a $400 million deal to buy the injectables formulations division of India's Orchid Pharma in 2009 and followed it up with the acquisition of a modern betalactam APIs plant and an associated R&D center for another $200 million three years later.
Flavone markedly affects phenotypic expression of betalactam resistance in methicillin-resistant Staphylococcus aureus strains isolated clinically.
The characteristics of imaging features contribute to the early diagnosis, and percutaneous intervention combined with an aminoglycoside plus either an extended-spectrum betalactam, such as piperacillin/sulbactam or a second- or third-generation cephalosporin, is a timely and effective treatment of KLA.