Four of the five beta-adrenergic blockers have no human eye data: betaxolol (Betoptic), carteolol (Ocupress), levobunolol (Betagan
), and metipranolol, but there are two case reports for timolol (Betimol, Istalol, Timoptic, Timoptic-XE) showing no fetal harm in one newborn and growth restriction in the other.
The antiglaucoma beta blockers include betaxolol (Betoptic), carteolol (Ocupress), levobetaxolol (Betaxon), levobunolol (Betagan
), metipranolol (Optipranolol) and timolol (Betimol, Timoptic, Istalol).
GLAUCOMA EYE DROPS Drug Names Action Side Effects Contraindications Betagan
, Reduces Difficulty Asthma, Betimol, production breathing, slowed bronchitis, Timoptic, of aqueous pulse, hair loss, chronic Ocupress, humor lower blood obstructive OptiPranolol pressure, pulmonary disease impotence, (COPD), heart fatigue, failure, weakness, emphysema, or depression, diabetes treated memory loss with insulin.
They are the respective generic equivalents to Betoptic and Betagan
Q I TAKE HRT, evening primrose, magnesium, vitamin B complex and vitamin C, Betagan
eye drops and Latanpost eye drops.
Non-selective beta-blockers such as timolol (Timoptic) and levobutonol (Betagan
) act on both ([[beta].sub.1]) (also situated in cardiac tissue) and ([[beta].sub.2]) (also present in the pulmonary system) receptors whereas selective beta-blockers, such as betaxolol (Betoptic) only act on ([[beta].sub.1]) receptors.
These drugs include beta-blockers like levobunolol (Betagan
), alpha-receptor agonists like brimonidine (Alphagan), and prostaglandin analogs like latanoprost (Xalatan).
For example, Allergan received its first generic competition to its Betagan
and Propine glaucoma treatments, causing the company to launch its own generic versions of these products through a collaborative effort with Schein Pharmaceutical Inc.; and Alcon Laboratories recently released a new prescription drug, Alomide, to treat vernal conjunctivitis.
Although prescribers could turn to alternative preservative-free beta-blockers such as betaxolol (Betoptic), levobunolol (Betagan
) or, following its launch in October 2011, the low-strength timolol preservative-free gel Tiopex for patients on Timoptol preservative-free, there was no alternative for patients on the other products, necessitating a review of treatment.