beta-lactam antibiotic


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beta-lactam antibiotic

n.
Any of a class of broad-spectrum antibiotics, such as the penicillins and the cephalosporins, that contain a beta-lactam ring.

beta-lactam antibiotic

any of a group of antibiotics, including the cephalosporins and the penicillins, whose chemical structure contains a beta-lactam ring.

beta-lactam antibiotic

Any of the antimicrobial drugs, such as penicillins or cephalosporins, that kill germs by interfering with the synthesis of bacterial cell walls.
Synonym: beta-lactam
See also: antibiotic
References in periodicals archive ?
Unlike hospital strains, which typically are resistant to multiple antibiotics and can be shown by typing schemes to be related to other hospital strains, these so-called community strains have tended to be susceptible to other antibiotic classes and often are resistant only to beta-lactam antibiotics (1,2,9).
Beta-lactamase inhibitors are administered in combination with beta-lactam antibiotics to restore or extend their ability to treat bacterial infections caused by beta-lactamase producing, antibiotic-resistant bacteria.
In addition, later generations of beta-lactam antibiotics have broader spectrums of activity, which may obviate any benefit offered by adding aminoglycosides.
Modern strains of MRSA have become broadly resistant to antibiotics, including beta-lactam antibiotics, such as penicillins.
The altered penicillin-binding protein, designated PBP2a, is able to perform its cell-wall synthesis functions, but has low affinity and does not bind to beta-lactam antibiotics.
Neither macrolides, ketolides, or fluoroquinolones were superior to beta-lactam antibiotics.
The persistently negative blood culture results, combined with the development of petechiae and failure to improve on ceftriaxone, led us to consider the diagnosis of typhus rather than typhoid fever, since rickettsia are resistant to beta-lactam antibiotics (6).
Because of its rapid bactericidal action and unique mechanism of action, lysostaphin has the potential to augment vancomycin and beta-lactam antibiotics as first line treatment for S.
Because of its rapid bactericidal action and unique mechanism of action, we believe Lysostaphin has the potential to augment vancomycin and beta-lactam antibiotics as first line treatment for S.
The product candidate FAROM(TM) is expected to launch in early 1997 as the first oral beta-lactam antibiotics with penem-type.
Reportedly, this key research programme is aimed at tackling the threat posed by NDM-1 and other metallo-[sz]-lactamases, enzymes that make bacteria resistant to widely used beta-lactam antibiotics such as penicillin.
Similar to other beta-lactam antibiotics, it is time dependent and its antibacterial activity is related to the duration of the maintenance of its free concentration above the minimal inhibitory concentration (MIC) during each dosing interval (referred to as % of T>MIC).

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