beta barrel

(redirected from Beta-barrel)

beta barrel

A protein structural motif consisting of antiparallel beta strands that form a hydrophobic protein core with a large beta-sheet that twists and coils, resulting in a closed structure in which the first strand is hydrogen bonded to the last. Beta barrels are found in porins and transmembrane proteins and encoded by up to 3% of gram-negative bacterial genes.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
Mentioned in ?
References in periodicals archive ?
Table 1: Accuracy of medium-small size (less than fifteen strands) beta-barrel modeling from simulated density maps at 10 [Angstrom] resolution.
He, "Combining image processing and modeling to generate traces of beta-strands from cryo-EM density images of beta-barrels," in Proceedings of the 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC '14), pp.
Understanding the so-called "beta-barrel assembly machinery" (BAM) could provide a target for new antimicrobial drugs, say the researchers.
Figure 3 shows two typical results from ProBLM (helical and beta-barrel proteins).
If the surface is cylindrical, like a CNT, you get a variant called the beta-barrel," says Jagota.
The Dow Chemical Company (Midland, MI) has patented a method for inserting Mucin peptide epitopes into the coat protein of a plant virus (e.g., a comovirus such as CPMV) having a beta-barrel structure at an immunogenically effective site, such as in a loop connecting beta sheets or at/near the C-terminus.
coli show it has a typical lipocalin fold consisting of eight anti-parallel beta-strands that form a beta-barrel with a distinct binding pocket for a small molecule.