Beta-HCG


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Related to Beta-HCG: BHCG

cho·ri·on·ic go·nad·o·tro·pin (CG),

a glycoprotein with a carbohydrate fraction composed of d-galactose and hexosamine, extracted from the urine of pregnant women and produced by the placental trophoblastic cells; its most important role appears to be stimulation, during the first trimester, of ovarian secretion of the estrogen and progesterone required for the integrity of conceptus; it appears to play no significant role in the last two trimesters of pregnancy, as the estrogen and progesterone are then formed by the placenta. CG has luteinizing hormone activity and exerts its actions through luteinizing hormone receptors.

Beta-HCG (Beta-human chorionic gonadotropin)

A tumor marker associated with testicular cancer and tumors, such as choriocarcinoma and molar pregnancies, that begin in placental cells called trophoblasts.
Mentioned in: Tumor Markers
References in periodicals archive ?
Another statistical measure, the area under the receiver operating curve (AUC), helps estimate the likelihood of EP according to beta-HCG levels.
Patients who satisfied the selection criteria were treated with single dose of IM methotrexate, followed with regular measurement of beta-hCG on day 1, 4, 7.
It has been suggested that these cysts arise from an abnormal response of atretic follicles in the ovaries to circulating Beta-hCG, which may or may not be high.
The neoplastic cells were positive for pan-cytokeratin (CK) and CK7 and showed focally immunoreactivity for beta-hCG [Figure 5] and human epidermal growth factor receptor 2 (Her-2) [Figure 6].
A large retrospective study of viable pregnancies showed that the median slope for the rise of serum beta-hCG was 2.
Stability of intact chorionic gonadotropin (hCG) in serum, liquid whole blood, and dried whole-blood filter-paper spots: impact on screening for Down syndrome by measurement of free beta-hCG subunit.
Trophoblastic tissue secretes beta-hCG and the differential diagnosis for an elevated serum HCG concentration includes intra-uterine and extra-uterine pregnancy, gestational trophoblastic neoplasia, and ovarian germ cell tumors.
In natural, with start the first week of conception and embryo's nesting in womb's wall, the amount of beta-HCG is increase enough, it can measure in serum.
Tertiary structures of beta-FSH and beta-HCG are superimposed in the structure window.
Although levels of free beta-hCG in affected pregnancies were higher earlier than the levels of either total hCG or inhibin A, there was no significant difference in screening performance when either of the three markers was used with nuchal translucency and PAPP-A at 11-13 weeks of pregnancy.
Concerns that the antibody response to beta-hCG may have the potential to cross-react with and interrupt other hormones produced in the pituitary gland have slowed the progress of anti-hCG clinical research.

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