ADRB2

(redirected from Beta-2 adrenoceptor)

ADRB2

A gene on chromosome 5q31-q32 that encodes beta-2-adrenergic receptor, a member of the G protein-coupled receptor superfamily, which mediates catecholamine-induced activation of adenylate cyclase. ADRB2 binds epinephrine with a 30-fold greater affinity than it does with norepinephrine.
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(1999) Lack of association between a human beta-2 adrenoceptor gene polymorphism (gln27glu) and morbid obesity.
(1997) Human beta-2 adrenoceptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoceptor function.