ADRB1

(redirected from Beta-1 adrenoceptor)

ADRB1

A gene on chromosome 10q24-q26 that encodes beta-1-adrenergic receptor, a member of the G protein-coupled receptor superfamily, which mediates catecholamine-induced activation of adenylate cyclase. ADRB1 binds epinephrine and norepinephrine with the same affinity.
References in periodicals archive ?
DCM had multiple potential causes, but one team had found a strong association between HLA-DR4 positive DCM and having beta-1 adrenoceptor autoantibodies, "72% of the HLA-DR4 dilated cardiomyopathy patients had anti-beta-receptor antibodies compared to 22% HLA-DR4-negative patients; conversely, 67% of the antibody-positive patients were typed as HLA-DR4 compared to only 10% of the antibodynegative patients.