adrenergic receptor

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Related to Beta adrenergic: Alpha adrenergic

Adrenergic Receptor

Any of a family of G protein-coupled cell membrane receptors which receive neuronal impulses from postganglionic adrenergic fibres of the sympathetic nervous system, which are divided into:
(1) Alpha receptors, which evoke an excitatory response of smooth muscle cells to catecholamines. Alpha receptors are divided into alpha1 (Gq) and alpha2 (Gi) coupled receptors.
Selective agonist, alpha receptor Phenylephrine
Alpha receptor effects Vasoconstriction, reduced GI tract motility.
(2) Beta receptors, which dampen the response to catecholamines. Beta receptors are divided into beta1, beta2, beta3, which are linked to Gs, and adenylate cyclase, increasing cAMP, which in turn drives cAMP-dependent protein kinase that mediates intracellular events.
Selective agonist, beta receptor Isoprenaline
Beta receptor effects Increased cardiac output, increased renin secretion from juxtaglomerular cells, increased gastric ghrelin secretion, smooth muscle relaxation resulting in bronchodilation, reduced GI motility, relaxation of detrusor muscle of the bladder, lipolysis, glycogenolysis and gluconeogenesis, increased renin secretion, insulin secretion, vasodilation, anabolism and thermogenesis of skeletal muscle.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

adrenergic receptor

Neurophysiology Any of a family of cell membrane receptors that receive neuronal impulses from postganglionic adrenergic fibers from the sympathetic nervous sytem, which are divided into α receptors, which results in an excitatory response of smooth muscle cells to catecholamines, and β receptors, which result in an inhibitory response to catecholamines; the GI tract is an exception, in that either α or β receptor stimulation results in relaxation
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

Adrenergic receptor

There are three families of adrenergic receptors, alpha1, alpha2 and beta, and each family contains three distinct subtypes. Each of the nine subtypes are coded by separate genes, and display specific drug specificities and regulatory properties.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
This report highlights the importance of a systematic approach to the evaluation of anisocoria and sensitises physicians to the phenomenon of potentiation of the beta adrenergic mydriatic effect of the commonly used nebulisers.
MAINTENANCE OF BETA ADRENERGIC RECEPTOR SIGNALING IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS.
Heart beats in all mammals are stimulated by the binding of catecholamine to beta adrenergic receptors in these cardiac cells.
Beta adrenergic inhibition of capsaicin-induced, NK1 receptor-mediated nerve growth factor biosynthesis in rat skin.
Use of Advair more than twice daily is not recommended because excessive beta adrenergic stimulation can occur with high doses of salmeterol.
Beta blockers (beta adrenergic antagonists) have, since their first day of introduction, been recognized to cause asthma.