human chorionic gonadotropin

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gonadotropin

 [go´nah-do-tro″pin]
any hormone having a stimulating effect on the gonads. Two such hormones are secreted by the anterior pituitary gland: follicle-stimulating hormone and luteinizing hormone, both of which are active, but with differing effects, in the two sexes. Called also gonadotropic hormone.
chorionic gonadotropin (human chorionic gonadotropin (HCG) (hCG))
1. a glycopeptide hormone that is produced by cells of the fetal placenta and maintains the function of the corpus luteum during the first few weeks of pregnancy. It is thought to promote steroidogenesis in the fetoplacental unit and to stimulate fetal testicular secretion of testosterone. It can be detected by immunoassay in the maternal urine within days after fertilization; this provides the basis for the most commonly used pregnancy test.
2. the same principle obtained from the urine of pregnant women, used in treatment of certain cases of cryptorchidism and male hypogonadism, to induce ovulation and pregnancy in certain infertile, anovulatory women, and to increase the numbers of oocytes for patients attempting conception using assisted reproductive technologies such as gamete intrafallopian transfer or in vitro fertilization; administered intramuscularly. See also choriogonadotropin alfa.

cho·ri·on·ic go·nad·o·tro·pin (CG),

a glycoprotein with a carbohydrate fraction composed of d-galactose and hexosamine, extracted from the urine of pregnant women and produced by the placental trophoblastic cells; its most important role appears to be stimulation, during the first trimester, of ovarian secretion of the estrogen and progesterone required for the integrity of conceptus; it appears to play no significant role in the last two trimesters of pregnancy, as the estrogen and progesterone are then formed by the placenta. CG has luteinizing hormone activity and exerts its actions through luteinizing hormone receptors.

human chorionic gonadotropin

n. Abbr. HCG
A hormone produced by the placenta that maintains the corpus luteum during pregnancy.

human chorionic gonadotropin

See hCG.

cho·ri·on·ic go·nad·o·tro·pin

(kōr'ē-on'ik gō-nad'ō-trō'pin)
A glycoprotein with a carbohydrate fraction composed of d-galactose and hexosamine, produced by the placental trophoblastic cells; its most important role appears to be stimulation (during the first trimester) of ovarian secretion of the estrogen and progesterone required for the integrity of the conceptus; it appears to play no significant role in the last two trimesters of pregnancy, because the estrogen and progesterone are then formed by the placenta. Testing for the beta fraction of human chorionic gonadotropin is the basis for most serum and urine pregnancy tests.
Synonym(s): anterior pituitarylike hormone, chorionic gonadotropic hormone, chorionic gonadotrophic hormone.

human chorionic gonadotropin (HCG)

a gonadotrophic hormone secreted by the chorion of the PLACENTA (1) that has a similar effect to luteinizing hormone (see LH).

Human chorionic gonadotropin (hCG)

A hormone excreted during the development of an embryo or fetus.

Patient discussion about human chorionic gonadotropin

Q. Does a slow rise in HCG hormone during pregnancy a condition to worry? My wife is in second trimester of pregnancy and had a HCG test, which shows fewer levels as compared to previous results. Does a slow rise in HCG hormone during pregnancy a condition to worry?

A. When you have a hCG test in the start of pregnancy, the level of hCG in your blood must increase to double in 2-3 days. While the hCG doubling time will slow down from the mid of the first trimester and hCG level also begin to slowly reduce from 4th month onwards. Thus at this stage there is nothing to worry about, it is normal.

More discussions about human chorionic gonadotropin
References in periodicals archive ?
Currently, hCG is the only biomarker used in clinical practise and initial serum beta hCG level is known to be the single best prognostic indicator of successful follow-up and treatment for single dose MTX.13 The more beta hCG level gets higher the more failure rates get higher.13 However, a test which may help to predict and facilitate the decision for treatment options has not been identified yet.
It also has variegated presentation as in our case as abdominal pain with elevated beta HCG, mimicking an ectopic pregnancy.
13 statement, the Kenyan bishops again referred to Mexico, Nicaragua and the Philippines, where they said "tetanus vaccination campaigns sponsored and funded by WHO and UNICEF were found to be poisoned with Beta HCG."
Clinical characteristics were summarised in terms of frequencies and percentages for qualitative variables (age group), mean standard deviation for continuous/quantitative variables (p level at D1, D5; E2 level at D1, D5; and beta hCG, etc).
In pregnancies with an unaffected female fetus, MSAFP has been reported to be significantly lower (3 percent) than in the presence of a male fetus; free beta hCG levels are higher (7 percent) if the fetus is female.
The diagnosis depends on a combination of ultrasound scan and serial serum beta HCG measurement.
In the same maternal plasma, we also measured the human chorionic gonadotropin-[beta] (hCG[beta]) concentration using the Ball ELSA Free Beta HCG reagent set (CIS Bio International).
The subject of the public procurement within this section is the supply of diagnostic kits for the spectrum of analytes (Free beta HCG, PAPP-A, Antigen SCC, Chromogranin), including the supply of the necessary consumables and calibrators.
One Salpingectomy Specimen showing Molar changes on histopathology followed up by normal beta HCG Regression curve.
Despistage de la trisomie 21 a I'aide de la beta hCG libre: notre experience sur trois ans.
Weekly follow up with beta HCG levels and ultra sound examination are important as low and declining beta HCG levels are not always associated with resolution of ectopic gestation and rupture can occur during conservative management.
The effect of thermal instability of intact human chorionic gonadotropin (ihCG) on the application of its free bet[alpha]-subunit (free beta hCG) as a serum marker in Down syndrome screening.