ubenimex

(redirected from Bestatin)

ubenimex

Alternative oncology
A competitive protease-inhibiting peptide isolated from the supernatant broth of cultured Streptomyces olivoreticuli that inhibits aminopeptidases B and N and leukotriene A4 hydrolase. Ubenimex stimulates the immune system, activates macrophages, increases production and secretion of IL-1 and IL-2, and stimulates T cells and haematopoiesis. It is in clinical trials for acute myeloid leukaemia and may be effective in treating various cancers, including Hodgkin lymphoma, leukaemia, melanoma, and cancers of the bladder, oesophagus, head and neck, lung and stomach.
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The effects of bestatin on humoral response to sheep erythrocytes in non- treated and cyclophosphamide- immunocompromised mice.
INFLUENCE OF ZHUQIN FORMULA EXTRACT ON THE CELLULAR AND HUMORAL IMMUNE RESPONSE IN CYCLOPHOSPHAMIDE-IMMUNOCOMPROMISED MICE
5% deoxycholate, 1 mM PMSF and protease inhibitor cocktail (2 mM [4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride], 14 [micro]M (N-(trans-epoxysuccinyl)-L-leucine 4-guanidinobutylamide], 130 [micro]M bestatin, 0.
Antidiabetic effects of the Cimicifuga racemosa extract Ze 450 in vitro and in vivo in ob/ob mice
Effect of protease inhibitors on endogenous or exogenous [beta]-galactosidase in human fibroblasts Inhibitor Protease [beta]- [beta]- Galactosidase Galactosidase (endogenous) * (exogenous) ** None 100 100 E-64 Thiol 430 229 (Cysteine) *** Leupeptin Thiol 460 222 (Cysteine) *** Antipain Thiol 490 224 (Cysteine) *** Chymostatin Thiol 520 188 (Cysteine) *** Elastatinal Elastase 60 103 Pepstatin Pepsin 100 97 Phosphoramidon Metallopeptidase 110 88 Bestatin Aminopeptidase 110 90 * Relative enzyme activity in human fibroblasts with cathepsin A deficiency (galactosialidosis).
Emerging novel concept of chaperone therapies for protein misfolding diseases
1]); the amino-peptidase inhibitor bestatin (50 [micro] mol [l.
Interaction of pathogenic vibrio bacteria with the blood clot of the pacific white shrimp, litopenaeus vannamei
Synthesis and structure-activity relationships of bestatin analogues, inhibitors of aminopeptidase.
3'-RACE amplification of Aminopeptidase N gene from Anopheles stephensi applicable in Transmission Blocking Vaccines
1% sodium dodecyl sulfate) containing 100 mM sodium orthovanadate and a protease inhibitor cocktail containing 4-(2-aminoethyl benzenesulfonyl fluoride), pepstatin A, E-64, bestatin, leupeptin, and aprotinin (Sigma).
Environmental levels of para-nonylphenol are able to affect cytokine secretion in human placenta
Dicho buffer estuvo compuesto de: 50 mM Tris-HCI (pH 8,0), 1 mM EDTA, 500 mM KCl, 2 mM ditiotreitol (DTT), y 0,05% coctel inhibidor de la proteasas (4-2-aminoetilbenzenesulfonil fluoride, pepstatin A, trans-epoxysuccinil-L-leucilamido 4-guanidino butano, bestatin, leupeptin y aprotinin; Sigma, St.
Deteccion de la subunidad NMDAR-1 del receptor N-metil-D-asparato (NMDAR) en el hipotalamo del ovino mediante el analisis de Western blot
Randomized double-blind placebo-controlled trial of bestatin in patients with resected stage I squamous-cell lung carcinoma.
Cancer de pulmon no microcitico: quimioterapia y otros tratamientos sistemicos
Genco found that, in test tube experiments, bestatin does not affect chemotaxis in neutrophils from healthy subjects, but it almost doubles the chemotactic activity in neutrophils from LJP patients.
Mouth immunity; an immune deficiency is associated with a rare periodontal disease
3 g/1 g of tissue of 4-(2- aminoethyl) benzenesulfonyl fluoride, bestatin, pepstatin A, E-64, leupeptin, 1,10-phenanthroline (Sigma, St.
RESPONSE OF CITRUS ROOTSTOCKS TO DIFFERENT SALINITY LEVELS FOR MORPHOLOGICAL AND ANTIOXIDATIVE ENZYME ACTIVITES
The protease inhibitors initially surveyed were antipain, aprotinin, bestatin, chymostatin, leupeptin, aminoethylbenzenesulfonyl fluoride (AEBSF), and phosphoramidon.
Reversible Alteration of Morphology in an Invertebrate Erythrocyte: Properties of the Natural Inducer and the Cellular Response
Bestatin was from Cambridge Research Biochemicals (Wilmington, DE).
Characterization and solubilization of the FMRFamide receptor of squid

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