verteporfin

(redirected from Benzoporphyrin derivative)

verteporfin

 [ver″tĕ-por´fin]
a photosensitizing agent that accumulates preferentially in neovasculature, including that in the choroid, such as occurs in age-related macular degeneration, ocular histoplasmosis, or pathologic myopia; the agent is then activated by light of a specific wavelength in the presence of oxygen, and causes local damage to the neovascular endothelium followed by vessel occlusion; it is administered intravenously prior to irradiation of the lesion with light from a compatible laser.

ver·te·por·fin

(vĕr-tē-pōr'fin),
Photosensitizer agent used in photodynamic therapy to treat choroidal neovascularization secondary to age related macular degeneration.
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The photosensitizer drugs segment is further categorized into Hematoporphyrin derivative (HpD), Aminolevulinic acid (ALA), Benzoporphyrin derivative (BPD), Texaphyrins, Chlorins and Dyes.
Photodynamic Therapy Market Analysis, Size, Share, Growth and Opportunity Assessment till 2029
Verteporfin (benzoporphyrin derivative monoacid ring A) is a derivative of PpIX that has been approved for clinical use.
Are two photons better than one? Two-photon excitation is a new paradigm in photodynamic therapy, and Canadian research is on top of the latest developments. (Articles)
Four photosensitizing drugs, Photofring, Texas Red, a benzoporphyrin derivative monoacid (BPD), and lutetium texaphyrin (LuTex) were tested to see if they were substrates of the MDR-1 multidrug resistor pump, or if they could be used in PDT.
Analysis of Photosensitizer Uptake in Roach Malpighian Tubules

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