benzodiazepine receptor

benzodiazepine receptor

Any of a number of different receptors for benzodiazepine identified in the brain. BZ-1 receptors may affect neural pathways involved in normal sleep patterns, while BZ-2 receptors are involved in memory and motor functions.
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However, the benzodiazepine receptor agonists such as zaleplon, Zolpidem, and eszopiclone, while lacking evidence in the pediatric population, may be worthwhile considerations as their varying half-lives allow for specificity in treating sleep-onset vs.
Insomnia--going beyond sleep hygiene
Patients met Beers CNS polypharmacy criteria if three or more of the following medications were initiated or continued: antipsychotics, benzodiazepines, nonbenzodiazepine benzodiazepine receptor agonists, tricyclic antidepressants, selective serotonin reuptake inhibitors, and opioids.
Outpatient visits for CNS polypharmacy up among elderly
Charney, "Decreased benzodiazepine receptor binding in prefrontal cortex in combat-related posttraumatic stress disorder," American Journal of Psychiatry, vol.
Effects of Traumatic Stress Induced in the Juvenile Period on the Expression of Gamma-Aminobutyric Acid Receptor Type A Subunits in Adult Rat Brain
Vomero et al., "Molecular basis of peripheral vs central benzodiazepine receptor selectivity in a new class of peripheral benzodiazepine receptor ligands related to alpidem," Journal of Medicinal Chemistry, vol.
TSPO PET Imaging: From Microglial Activation to Peripheral Sterile Inflammatory Diseases?
Guilarte et al., "Translocator protein (18 kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function," Trends in Pharmacological Sciences, vol.
Adrenal Oncocytic Neoplasm with Paradoxical Loss of Important Mitochondrial Steroidogenic Protein: The 18 kDA Translocator Protein
Gamma-aminobutyric acidA receptor alpha 5-subunit creates novel type II benzodiazepine receptor pharmacology.
Using benzodiazepine detoxification and cognitive behavioral psychotherapy in the treatment of a patient with generalized anxiety disorder comorbid with high-dose zolpidem dependence
All FDA-approved benzodiazepine receptor agonists work on GABAA receptors; therefore, the difference among them is half-life.
Solving clinical challenges, improving patient care
Of special interest is Rozerem is not expected to exhibit rebound insomnia, memory impairment, respiratory depression, drug abuse, dependence, and withdrawal as by some of the benzodiazepine receptor agonists.
Melatonin revisted
Therefore, we used a classic benzodiazepine drug association protocol and a [GABA.sub.A] benzodiazepine receptor site antagonist, flumazenil, for CNS depression reversal.
Effect of (+)-dehydrofukinone on GABA A receptors and stress response in fish model
Overview-flavonoids: a new family of benzodiazepine receptor ligands.
Anxiolytic and sedative-like effects of flavonoids from Tilia americana var. mexicana: GABAergic and serotonergic participation
The 18 kDa translocator protein [1] (TSPO; previously-known as the peripheral benzodiazepine receptor, PBR) has been extensively studied for its intricate biological functions.
Radiosynthesis, in vivo biological evaluation, and imaging of brain lesions with [[sup.123]I]-CLINME, a new SPECT tracer for the translocator protein
angustifolia has been found to contain flavonoid components and some flavones, such as chrysin, (5, 7-dihydroxyflavone) which have a partial agonistic effect on benzodiazepine receptors. Central benzodiazepine receptor (BDZ-R) agonists have been known to induce multiple effects including anxiolytic, myorelaxant, anticovulsant, hypnotic and amnestic effects (44-46).
Comparison of Elaeagnus angustifolia extract and sildenafil citrate on female orgasmic disorders: a randomized clinical trial

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